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Substance Name: Lumefantrine [USAN:INN:BAN]
RN: 82186-77-4
UNII: F38R0JR742
InChIKey: DYLGFOYVTXJFJP-MYYYXRDXSA-N

Note

  • Artemether-lumefantrine combination is treatment of choice for adults in Zambia.

Molecular Formula

  • C30-H32-Cl3-N-O

Molecular Weight

  • 528.9478
 

Classification Codes

  • Anti-Infective Agents
  • Antimalarial
  • Antimalarials
  • Antiparasitic Agents
  • Antiprotozoal Agents
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Names and Synonyms

Name of Substance

  • Benflumetol
  • Lumefantrine
  • Lumefantrine [USAN:INN:BAN]

Synonyms

  • (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha((dibutylamino)methyl)fluorene-4-methanol
  • (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
  • dl-Benflumelol
  • HSDB 7210
  • Lumefantrine
  • UNII-F38R0JR742

Systematic Name

  • 9H-Fluorene-4-methanol, 2,7-dichloro-9-((4-chlorophenyl)methylene)-alpha-((dibutylamino)methyl)-, (Z)-

Mixture Name

  • Coartem

Registry Numbers

CAS Registry Number

  • 82186-77-4

FDA UNII

  • F38R0JR742

Other Registry Number

  • 120583-69-9

System Generated Number

  • 0082186774

Structure Descriptors

InChI

1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-

InChIKey

DYLGFOYVTXJFJP-MYYYXRDXSA-N

Smiles

CCCCN(CCCC)CC(O)c1cc(Cl)cc2\C(=C/c3ccc(Cl)cc3)\c4cc(Cl)ccc4c12