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Substance Name: Carbetimer [USAN:INN]
RN: 82230-03-3
UNII: A678KM0M0N

Note

  • Partially imidized copolymer of ethylene & maleic anhydride with average MW approx 1,200 daltons; capable of specific stimulation of immune response.

Molecular Weight

  • 523.583
 

Classification Codes

  • Adjuvants, Immunologic
  • Antineoplastic
  • Antineoplastic Agents
  • Drug / Therapeutic Agent
  • Immunologic Factors
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Links to Resources

Names and Synonyms

Name of Substance

  • Carbetimer [USAN:INN]
  • Carboxyimamidate

Synonyms

  • Carbetimer
  • Carbetimere
  • Carbetimere [French]
  • Carbetimero
  • Carbetimero [Spanish]
  • Carbetimerum
  • Carbetimerum [Latin]
  • Maleic anhydride polymer with ethylene, reaction product with ammonia
  • N-137
  • NSC 329514D
  • UNII-A678KM0M0N

Systematic Names

  • 2,5-Furandione polymer with ethene, reaction product with ammonia
  • Carbetimer

Registry Numbers

CAS Registry Number

  • 82230-03-3

FDA UNII

  • A678KM0M0N

System Generated Number

  • 0082230033

Structure Descriptors

Smiles

C1(NC([C@@H]([C@@H]1CC[C@@H](C(=O)N)[C@@H](CC[C@@H](C(N)=O)CC([O-])=O)C(=O)[O-])[C@@H](c1ccccc1)C)=O)=O.[NH4+].[NH4+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1757mg/kg (1757mg/kg)   Cancer Research. Vol. 48, Pg. 5353, 1988.