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Substance Name: Cefteram pivoxil [JAN]
RN: 82547-81-7
UNII: 0OD86RT58C
InChIKey: UIYAXIPXULMHAI-JLGRZTKVSA-N

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C22-H27-N9-O7-S2

Molecular Weight

  • 593.6433
 
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Names and Synonyms

Name of Substance

  • Cefteram pivaloyloxymethyl ester
  • Cefteram pivoxil
  • Cefteram pivoxil [JAN]

Synonyms

  • BRN 4223783
  • Cefteram pivoxil
  • T-2588
  • Tomiron
  • UNII-0OD86RT58C

Systematic Name

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((5-methyl-2H-tetrazol-2-yl)methyl)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R-(6-alpha,7-beta(Z)))-

Registry Numbers

CAS Registry Number

  • 82547-81-7

FDA UNII

  • 0OD86RT58C

System Generated Number

  • 0082547817

Structure Descriptors

InChI

1S/C22H27N9O7S2/c1-10-26-29-30(27-10)6-11-7-39-18-14(25-16(32)13(28-36-5)12-8-40-21(23)24-12)17(33)31(18)15(11)19(34)37-9-38-20(35)22(2,3)4/h8,14,18H,6-7,9H2,1-5H3,(H2,23,24)(H,25,32)/b28-13-/t14-,18-/m1/s1

InChIKey

UIYAXIPXULMHAI-JLGRZTKVSA-N

Smiles

CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)Cn3nnc(C)n3)\c4csc(N)n4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 2gm/kg (2000mg/kg)   Chemotherapy Vol. 34(Suppl,
mouse LD50 intraperitoneal 5860mg/kg (5860mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Chemotherapy Vol. 34(Suppl,
mouse LD50 oral > 6gm/kg (6000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Chemotherapy Vol. 34(Suppl,
mouse LD50 subcutaneous > 6gm/kg (6000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Chemotherapy Vol. 34(Suppl,
rat LD50 intraperitoneal 5090mg/kg (5090mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Chemotherapy Vol. 34(Suppl,
rat LD50 oral > 6gm/kg (6000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Chemotherapy Vol. 34(Suppl,
rat LD50 subcutaneous > 6gm/kg (6000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Chemotherapy Vol. 34(Suppl,