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Substance Name: Quinapril hydrochloride [USAN:USP]
RN: 82586-55-8
UNII: 33067B3N2M
InChIKey: IBBLRJGOOANPTQ-JKVLGAQCSA-N
Molecular Formula
- C25-H30-N2-O5.Cl-H
Molecular Weight
- 474.982
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Angiotensin-Converting Enzyme Inhibitors
- Antihypertensive
- Antihypertensive Agents
- Cardiovascular Agents
- Drug / Therapeutic Agent
- Enzyme Inhibitor (Angiotensin-Converting)
- Enzyme Inhibitors
- Protease Inhibitors
- Reproductive Effect
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Names and Synonyms
Name of Substance
- Quinapril hydrochloride
- Quinapril hydrochloride [USAN:USP]
Synonyms
- (S)-2-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride
- 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))
- Accupril
- Accuprin
- Accupron
- Acequin
- Acuitel
- Acuprel
- Asig
- CI-906
- CI906
- Conan
- Continucor
- Ectren
- Hemokvin
- HSDB 7046
- Korec
- Koretic
- Lidaltrin
- NSC 758222
- PD 109452-2
- Quinapril
- Quinapril HCl
- Quinapril hydrochloride
- Quinazil
- UNII-33067B3N2M
Systematic Names
- 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (3S-(2(R*(R*)),3R*))-
- 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))
Mixture Name
- Accuretic
Registry Numbers
CAS Registry Number
- 82586-55-8
FDA UNII
- 33067B3N2M
System Generated Number
- 0082586558
Molecular Formulas
Molecular Formula
- C25-H30-N2-O5.Cl-H
Molecular Formula Fragments
- C25-H30-N2-O5
- Cl-H
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1InChIKey
IBBLRJGOOANPTQ-JKVLGAQCSA-NSmiles
Cl.CCOC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD | oral | > 500mg/kg (500mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995. | |
mouse | LD50 | intravenous | 504mg/kg (504mg/kg) | Angiology. Vol. 40, Pg. 335, 1989. | |
mouse | LD50 | oral | 1739mg/kg (1739mg/kg) | Angiology. Vol. 40, Pg. 335, 1989. | |
rat | LD50 | intravenous | 107mg/kg (107mg/kg) | Angiology. Vol. 40, Pg. 335, 1989. | |
rat | LD50 | oral | 3541mg/kg (3541mg/kg) | Angiology. Vol. 40, Pg. 335, 1989. |