Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Flurithromycin [INN]
RN: 82664-20-8
UNII: 56C9DTE69V
InChIKey: XOEUHCONYHZURQ-HNUBZJOYSA-N

Note

  • Fluorine derivative of erythromycin.

Classification Codes

  • Drug / Therapeutic Agent
  • Enzyme Inhibitors

Molecular Formula

  • C37-H66-F-N-O13

Molecular Weight

  • 751.92
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Flurithromycin
  • Flurithromycin [INN]

Synonyms

  • (8S)-8-Fluoroerythromycin A
  • 8-Fluoroerythromycin
  • Antibiotic P 80206
  • Cl-932
  • Flurithromycin
  • Flurithromycine
  • Flurithromycine [French]
  • Fluritromicina
  • Fluritromicina [Spanish]
  • Fluritromycinum
  • Fluritromycinum [Latin]
  • P 80206
  • P-0501A
  • UNII-56C9DTE69V

Systematic Names

  • (8S)-8-Fluoroerythromycin
  • Erythromycin, 8-fluoro-

Registry Numbers

CAS Registry Number

  • 82664-20-8

FDA UNII

  • 56C9DTE69V

System Generated Number

  • 0082664208

Structure Descriptors

InChI

1S/C37H66FNO13/c1-14-24-37(10,46)29(42)21(5)28(41)34(7,38)17-35(8,45)31(52-33-26(40)23(39(11)12)15-18(2)48-33)19(3)27(20(4)32(44)50-24)51-25-16-36(9,47-13)30(43)22(6)49-25/h18-27,29-31,33,40,42-43,45-46H,14-17H2,1-13H3/t18-,19+,20-,21+,22+,23+,24-,25+,26-,27+,29-,30+,31-,33+,34+,35-,36-,37-/m1/s1

InChIKey

XOEUHCONYHZURQ-HNUBZJOYSA-N

Smiles

O1[C@@H](O[C@@H]2[C@@H](C)C(=O)O[C@H](CC)[C@](C)([C@@H]([C@H](C(=O)[C@](C)(C[C@@](C)(O)[C@@H](O[C@@H]3O[C@@H](C[C@@H]([C@H]3O)N(C)C)C)[C@H]2C)F)C)O)O)C[C@@](OC)([C@H](O)[C@@H]1C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 790mg/kg (790mg/kg)   Journal of Antibiotics. Vol. 37, Pg. 84-108, 1984.
mouse LD50 oral 8100mg/kg (8100mg/kg)   Journal of Antibiotics. Vol. 37, Pg. 84-108, 1984.
rat LD50 intraperitoneal > 1500mg/kg (1500mg/kg)   Drugs of the Future. Vol. 12, Pg. 214, 1987.
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs of the Future. Vol. 12, Pg. 214, 1987.