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Substance Name: Nefazodone hydrochloride [USAN:USP]
RN: 82752-99-6
UNII: 27X63J94GR
InChIKey: DYCKFEBIOUQECE-UHFFFAOYSA-N

Note

  • May be useful as an opiate adjunct.

Molecular Formula

  • C25-H32-Cl-N5-O2.Cl-H

Molecular Weight

  • 506.475
 

Classification Codes

  • Antidepressant
  • Antidepressive Agents
  • Antidepressive Agents, Second-Generation
  • Central Nervous System Agents
  • Psychotropic Drugs

Names and Synonyms

Name of Substance

  • Nefazodone
  • Nefazodone hydrochloride [USAN:USP]

Synonyms

  • 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta(sup 2)-1,2,4-triazolin-5-one monohydrochloride
  • 3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl))propyl)-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride
  • BMY 13754
  • Dutonin
  • Menfazona
  • MJ 13,754-1
  • Nefazodone HCl
  • Nefazodone hydrochloride
  • NSC 760344
  • Reseril
  • Rulivan
  • Serzone
  • UNII-27X63J94GR

Systematic Name

  • 3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 82752-99-6

FDA UNII

  • 27X63J94GR

Related Registry Number

  • 83366-66-9 (Parent)

System Generated Number

  • 0082752996

Molecular Formulas

Molecular Formula

  • C25-H32-Cl-N5-O2.Cl-H

Molecular Formula Fragments

  • C25-H32-Cl-N5-O2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H

InChIKey

DYCKFEBIOUQECE-UHFFFAOYSA-N

Smiles

Cl.CCC1=NN(CCCN2CCN(CC2)c3cccc(Cl)c3)C(=O)N1CCOc4ccccc4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 1333ug/kg (1.333mg/kg) BEHAVIORAL: ATAXIA Veterinary and Human Toxicology. Vol. 41, Pg. 321, 1999.