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Substance Name: Tetrophan
RN: 83-93-2
UNII: 4U947K73Q2
InChIKey: QWNOQAWEROHNNQ-UHFFFAOYSA-N

Molecular Formula

  • C18-H13-N-O2

Molecular Weight

  • 275.306
 
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Names and Synonyms

Results Name

  • Tetrophan

Name of Substance

  • Tetrophan

Synonyms

  • 3,4-Dihydro-1,2-benzacridinic-5-carbonic acid
  • 4-22-00-01422 (Beilstein Handbook Reference)
  • 5,6-Dihydrobenz(c)acridine-7-carboxylic acid
  • BRN 0256492
  • Tetrofan
  • Tetrophan
  • UNII-4U947K73Q2

Systematic Name

  • Benz(c)acridine-7-carboxylic acid, 5,6-dihydro-

Registry Numbers

CAS Registry Number

  • 83-93-2

FDA UNII

  • 4U947K73Q2

System Generated Number

  • 0000083932

Structure Descriptors

InChI

1S/C18H13NO2/c20-18(21)16-13-7-3-4-8-15(13)19-17-12-6-2-1-5-11(12)9-10-14(16)17/h1-8H,9-10H2,(H,20,21)

InChIKey

QWNOQAWEROHNNQ-UHFFFAOYSA-N

Smiles

c1cc2c(cc1)c(c1CCc3c(c1n2)cccc3)C(O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo unreported 40mg/kg (40mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 27, 1955.
mouse LD50 intraperitoneal 760mg/kg (760mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 27, 1955.
rabbit LDLo intravenous 40mg/kg (40mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: TETANY

CARDIAC: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 371, 1955.