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Substance Name: Octreotide [USAN:INN:BAN]
RN: 83150-76-9
UNII: RWM8CCW8GP
InChIKey: DEQANNDTNATYII-OULOTJBUSA-N

Note

  • A potent, long-acting synthetic SOMATOSTATIN octapeptide analog that inhibits secretion of GROWTH HORMONE and is used to treat hormone-secreting tumors; DIABETES MELLITUS; HYPOTENSION, ORTHOSTATIC; HYPERINSULINISM; hypergastrinemia; and small bowel fistula.

Molecular Formula

  • C49-H66-N10-O10-S2

Molecular Weight

  • 1019.2524
 

Classification Codes

  • Antineoplastic Agents
  • Antineoplastic Agents, Hormonal
  • Antisecretory (Gastric)
  • Gastrointestinal Agents

Names and Synonyms

Name of Substance

  • Octreotide
  • Octreotide [USAN:INN:BAN]

MeSH Heading

  • Octreotide

Synonyms

  • D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
  • D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
  • DRG-0115
  • L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2-7)-disulfide, (R-(R*,R*))-
  • Longastatin
  • Octreotida
  • Octreotida [Spanish]
  • Octreotide
  • Octreotide-LAR
  • Octreotidum
  • Octreotidum [Latin]
  • Sandostatin
  • SMS-201-995
  • UNII-RWM8CCW8GP

Systematic Name

  • L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2-7)-disulfide, (R-(R*,R*))-

Registry Numbers

CAS Registry Number

  • 83150-76-9

FDA UNII

  • RWM8CCW8GP

Related Registry Number

  • 79517-01-4 (acetate salt)

System Generated Number

  • 0083150769

Structure Descriptors

InChI

1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1

InChIKey

DEQANNDTNATYII-OULOTJBUSA-N

Smiles

C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1