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Substance Name: Sargramostim
RN: 83869-56-1


  • An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

Molecular Formula

  • Unspecified

Classification Code

  • Antiviral (COVID-19)
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Links to Resources

Names and Synonyms

Name of Substance

  • Sargramostim

MeSH Heading

  • Granulocyte-macrophage colony-stimulating factor


  • Colony-stimulating factor II
  • Colony-stimulating factor, granulocyte-macrophage
  • CSF 2
  • Csf-GM
  • GM-CSF
  • Granulocyte-macrophage colony-stimulating activity
  • Granulocyte-macrophage colony-stimulating factor
  • Granulocyte-macrophage-inducing factor
  • Granulocyte-monocyte colony-stimulating factor
  • Histamine-producing cell-stimulating factor
  • Leukine
  • Macrophage-granulocyte CSF

Systematic Name

  • Colony-stimulating factor 2

Registry Numbers

CAS Registry Number

  • 83869-56-1

System Generated Number

  • 0083869561