Substance Name: Sargramostim
RN: 83869-56-1
Note
- An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
Molecular Formula
- Unspecified
Classification Code
- Antiviral (COVID-19)
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Sargramostim
MeSH Heading
- Granulocyte-macrophage colony-stimulating factor
Synonyms
- Colony-stimulating factor II
- Colony-stimulating factor, granulocyte-macrophage
- CSF 2
- Csf-GM
- GM-CSF
- Granulocyte-macrophage colony-stimulating activity
- Granulocyte-macrophage colony-stimulating factor
- Granulocyte-macrophage-inducing factor
- Granulocyte-monocyte colony-stimulating factor
- Histamine-producing cell-stimulating factor
- Leukine
- Macrophage-granulocyte CSF
Systematic Name
- Colony-stimulating factor 2
Registry Numbers
CAS Registry Number
- 83869-56-1
System Generated Number
- 0083869561