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Substance Name: Dibutyl phthalate [NF]
RN: 84-74-2
UNII: 2286E5R2KE
InChIKey: DOIRQSBPFJWKBE-UHFFFAOYSA-N

Note

  • A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.

Molecular Formula

  • C16-H22-O4

Molecular Weight

  • 278.3458
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Human Data
  • Insect Attractant, Repellent and Chemosterilant
  • Mutation Data
  • Plasticizers
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 52
  • 2011 CERCLA Priority List, Rank: 58
  • Reportable Quantity (RQ) = 10 lb
  • TWA 5 mg/m3

Names and Synonyms

Name of Substance

  • 1,2-Benzenedicarboxylic acid, dibutyl ester
  • Dibutyl 1,2-benzenedicarboxylate
  • Dibutyl phthalate
  • Dibutyl phthalate [NF]

MeSH Heading

  • Dibutyl phthalate

Synonyms

  • 1,2-Benzenedicarboxylic acid, dibutyl ester
  • 4-09-00-03175 (Beilstein Handbook Reference)
  • AI-3-00283
  • Benzene-o-dicarboxylic acid di-n-butyl ester
  • BRN 1914064
  • Butyl phthalate
  • Caswell No. 292
  • CCRIS 2676
  • Celluflex DPB
  • DBP
  • DBP (ester)
  • Di-n-butyl phthalate
  • Di-n-butylester kyseliny ftalove
  • Di-n-butylester kyseliny ftalove [Czech]
  • Dibutyl 1,2-benzenedicarboxylate
  • Dibutyl phthalate
  • Dibutyl-o-phthalate
  • EC 201-557-4
  • EINECS 201-557-4
  • Elaol
  • EPA Pesticide Chemical Code 028001
  • Ergoplast FDB
  • Ersoplast FDA
  • Genoplast B
  • Hatcol DBP
  • Hexaplas M/B
  • HSDB 922
  • Kodaflex DBP
  • n-Butyl phthalate
  • N-Butylphthalate
  • NSC 6370
  • o-Benzenedicarboxylic acid, dibutyl ester
  • Palatinol C
  • Phthalate, di-n-butyl
  • Phthalate, dibutyl-
  • Polycizer DBP
  • PX 104
  • RC Plasticizer DBP
  • RCRA waste number U069
  • Staflex DBP
  • Uniflex DBP
  • UNII-2286E5R2KE
  • Unimoll db
  • Witcizer 300

Systematic Names

  • 1,2-Benzenedicarboxylic acid, 1,2-dibutyl ester
  • 1,2-Benzenedicarboxylic acid, dibutyl ester
  • Dibutyl phthalate
  • Phthalic acid, dibutyl ester

Superlist Names

  • 1,2-Benzenedicarboxylic acid, dibutyl ester
  • Di-n-butyl phthalate
  • Dibutyl phthalate
  • n-Butyl phthalate
  • ortho-Dibutyl phthalate
  • Phthalic acid, dibutyl ester
  • RCRA waste no. U069

Registry Numbers

CAS Registry Number

  • 84-74-2

FDA UNII

  • 2286E5R2KE

System Generated Number

  • 0000084742

Structure Descriptors

InChI

InChI=1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3

InChIKey

DOIRQSBPFJWKBE-UHFFFAOYSA-N

Smiles

CCCCOC(=O)c1ccccc1C(=O)OCCCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 10gm/kg (10000mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 25, 1980.
guinea pig LD50 oral 10gm/kg (10000mg/kg) BEHAVIORAL: WITHDRAWAL

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 25, 1980.
human TDLo oral 140mg/kg (140mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

GASTROINTESTINAL: NAUSEA OR VOMITING

KIDNEY, URETER, AND BLADDER: OTHER CHANGES 		Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 1243, 1954.
mammal (species unspecified) LD50 oral 5gm/kg (5000mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LC50 inhalation 25gm/m3/2H (25000mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 44, 1982.
mouse LD50 intraperitoneal 3570mg/kg (3570mg/kg)   Journal of the Society of Cosmetic Chemists. Vol. 28, Pg. 667, 1977.
mouse LD50 intravenous 720mg/kg (720mg/kg)   Kanagawa-ken Eisei Kenkyusho Kenkyu Hokoku. Bulletin of Kanagawa Prefectural Public Health Laboratories. Vol. (3), Pg. 19, 1973.
mouse LD50 oral 3474mg/kg (3474mg/kg)   Weisheng Dulixue Zazhi. Journal of Health Toxicology. Vol. 5, Pg. 264, 1991.
mouse LD50 unreported 8140mg/kg (8140mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ATAXIA		 Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(6), Pg. 86, 1990.
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 12/29/1971,
rat LC50 inhalation 4250mg/m3 (4250mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(8), Pg. 26, 1973.
rat LD50 intramuscular > 8gm/kg (8000mg/kg)   "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1904, 1963.
rat LD50 intraperitoneal 3050uL/kg (3.05mL/kg)   Journal of Pharmaceutical Sciences. Vol. 61, Pg. 51, 1972.
rat LD50 oral 7499mg/kg (7499mg/kg)   Weisheng Dulixue Zazhi. Journal of Health Toxicology. Vol. 5, Pg. 264, 1991.
rat LD50 unreported 9410mg/kg (9410mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(6), Pg. 86, 1990.
rat LDLo skin 6gm/kg (6000mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 44, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -3.50E+01 deg C   EXP
Boiling Point 340 deg C   EXP
log P (octanol-water) 4.5 (none)   EXP
Water Solubility 11.2 mg/L 25 EXP
Vapor Pressure 2.01E-05 mm Hg 25 EXP
Henry's Law Constant 1.81E-06 atm-m3/mole 23 EXP
Atmospheric OH Rate Constant 9.28E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.