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Substance Name: Norcyclizine
RN: 841-77-0
InChIKey: NWVNXDKZIQLBNM-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H20-N2

Molecular Weight

  • 252.359
 
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Names and Synonyms

Name of Substance

  • Norcyclizine

Synonyms

  • 1-(Diphenylmethyl)piperazine
  • 1-Benzhydrylpiperazine
  • 4-Benzhydrylpiperazine
  • 5-23-01-00231 (Beilstein Handbook Reference)
  • Benzhydrylpiperazine
  • BRN 0222773
  • Diphenylmethylpiperazine
  • EINECS 212-667-7
  • N-(Diphenylmethyl)piperazine
  • N-Benzhydrylpiperazine
  • Norcyclizine
  • Normethylcyclizine
  • NSC 35536

Systematic Names

  • 1-Benzhydrylpiperazine
  • Piperazine, 1-(diphenylmethyl)-

Registry Numbers

CAS Registry Number

  • 841-77-0

Related Registry Number

  • 56609-03-1 (mono-hydrochloride)

System Generated Number

  • 0000841770

Structure Descriptors

InChI

1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2

InChIKey

NWVNXDKZIQLBNM-UHFFFAOYSA-N

Smiles

N1(C(c2ccccc2)c2ccccc2)CCNCC1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 38mg/kg (38mg/kg)   Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 31, Pg. 453, 1972.
mouse LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toksikologicheskii Vestnik. Vol. (2), Pg. 28, 1997.
rat LD50 oral 500mg/kg (500mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toksikologicheskii Vestnik. Vol. (2), Pg. 28, 1997.