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Substance Name: Mifepristone [USAN:INN:BAN]
RN: 84371-65-3
UNII: 320T6RNW1F
InChIKey: VKHAHZOOUSRJNA-GCNJZUOMSA-N
Note
- A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Molecular Formula
- C29-H35-N-O2
Molecular Weight
- 429.6005
Classification Codes
- Abortifacient Agents
- Abortifacient Agents, Steroidal
- Contraception
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral
- Contraceptives, Oral, Synthetic
- Contraceptives, Postcoital
- Contraceptives, Postcoital, Synthetic
- Hormone
- Hormone Antagonists
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Human Data
- Induction of Abortion
- Luteolytic Agents
- Menstruation-Inducing Agents
- Reproductive Control Agents
- Reproductive Effect
- Treatment of Gynecological Disorders (Progesterone Antagonist)
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Names and Synonyms
Name of Substance
- Mifepristone
- Mifepristone [USAN:INN:BAN]
MeSH Heading
- Mifepristone
Synonyms
- (11beta,17beta)-11-(4-(Dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one
- 11beta-(4-(Dimethylamino)phenyl)-17-hydroxy-21-methyl-19-nor-17alpha-pregna-4,9-dien-20-m-3-on
- 11beta-(4-(Dimethylamino)phenyl)-17beta-hydroxy-17-(1-propynyl)estra-4,9-dien-3-on
- 11beta-(4-(N,N-Dimethylamino)phenyl)-17alpha-(prop-1-ynyl)-delta4,9-estradiene-17beta-ol-3-one
- 11beta-(p-(Dimethylamino)phenyl)-17beta-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
- 17-beta-Hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oestra-4,9-dien-3-one
- BRN 5779404
- CCRIS 9332
- Corlux
- HSDB 6841
- Korlym
- Mifegyne
- Mifeprex
- Mifepristona
- Mifepristona [Spanish]
- Mifepristone
- Mifepristonum
- Mifepristonum [Latin]
- NSC 759862
- R 38486
- RU 38486
- RU 486
- RU 486-6
- UNII-320T6RNW1F
Systematic Names
- 11beta-(p-(Dimethylamino)phenyl)-17beta-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
- Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-, (11-beta,17-beta)-
Registry Numbers
CAS Registry Number
- 84371-65-3
FDA UNII
- 320T6RNW1F
Other Registry Numbers
- 122742-25-0
- 83203-42-3
System Generated Number
- 0084371653