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Substance Name: Raloxifene [INN:BAN]
RN: 84449-90-1
UNII: YX9162EO3I
InChIKey: GZUITABIAKMVPG-UHFFFAOYSA-N

Note

  • A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.

Molecular Formula

  • C28-H27-N-O4-S

Molecular Weight

  • 473.5903
 

Classification Codes

  • Anti-Estrogen
  • Bone Density Conservation Agents
  • Estrogen Antagonists
  • Estrogen Receptor Modulators
  • Hormone Antagonists
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Selective Estrogen Receptor Modulators

Names and Synonyms

Name of Substance

  • Raloxifene
  • Raloxifene [INN:BAN]

MeSH Heading

  • Raloxifene

Synonyms

  • (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone
  • CCRIS 7129
  • HSDB 7460
  • LY 139481
  • NSC 747974
  • Pharoxifene
  • Raloxifene
  • Raloxifeno
  • Raloxifeno [Spanish]
  • Raloxifenum
  • Raloxifenum [Latin]
  • UNII-YX9162EO3I

Systematic Names

  • Keoxifene
  • Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-

Registry Numbers

CAS Registry Number

  • 84449-90-1

FDA UNII

  • YX9162EO3I

Related Registry Number

  • 82640-04-8 (hydrochloride)

System Generated Number

  • 0084449901

Structure Descriptors

InChI

InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2

InChIKey

GZUITABIAKMVPG-UHFFFAOYSA-N

Smiles

Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4