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Substance Name: Textilotoxin
RN: 85666-96-2

Note

  • Isolated from venom of Australian brown snake (Pseudonaja textilis).
 

Classification Code

  • Natural Product
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Names and Synonyms

Name of Substance

  • Textilotoxin

Synonyms

  • Australian brown snake venom
  • Pseudonaja textilis venom
  • Textilon (Obs.)
  • Textilotoxin

Systematic Names

  • Textilotoxin
  • Venom, snake, Pseudonaja textilis

Registry Numbers

CAS Registry Number

  • 85666-96-2

System Generated Number

  • 0085666962

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo intramuscular 500ug/kg (0.5mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicon. Vol. 19, Pg. 749, 1981.
mouse LD50 intraperitoneal 310ug/kg (0.31mg/kg)   Toxicon. Vol. 17(Suppl,
mouse LD50 intravenous 1ug/kg (0.001mg/kg)   Toxicon. Vol. 21, Pg. 143, 1983.
mouse LD50 subcutaneous 41ug/kg (0.041mg/kg)   Toxicon. Vol. 17, Pg. 661, 1979.