Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Pheniramine [INN:BAN]
RN: 86-21-5
UNII: 134FM9ZZ6M
InChIKey: IJHNSHDBIRRJRN-UHFFFAOYSA-N

Note

  • One of the HISTAMINE H1 ANTAGONISTS with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.

Molecular Formula

  • C16-H20-N2

Molecular Weight

  • 240.348
 

Classification Codes

  • Anti-Allergic Agents
  • Antipruritics
  • Dermatologic Agents
  • Drug / Therapeutic Agent
  • Histamine Agents
  • Histamine Antagonists
  • Histamine H1 Antagonists
  • Human Data
  • Neurotransmitter Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Pheniramine [INN:BAN]

Name of Substance

  • Pheniramine
  • Pheniramine [INN:BAN]

MeSH Heading

  • Pheniramine

Synonyms

  • 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane
  • 2-(3-Dimethylamino-1-phenylpropyl)pyridine
  • 2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine
  • 2-Pyridinepropanamine, N,N-dimethyl-gamma-phenyl-
  • 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylanine
  • 5-22-10-00487 (Beilstein Handbook Reference)
  • BRN 0192445
  • EINECS 201-656-2
  • Feniramina
  • Feniramina [INN-Spanish]
  • Feniramine
  • N,N-Dimethyl-3-phenyl-3-(2-pyridyl)propylamine
  • NCI-C60695
  • NSC 47965
  • Pheniramine
  • Pheniraminum
  • Pheniraminum [INN-Latin]
  • Prophenpyridamine
  • Pyriton
  • Trimeton
  • Tripoton
  • UNII-134FM9ZZ6M

Systematic Names

  • 2-Pyridinepropanamine, N,N-dimethyl-gamma-phenyl- (9CI)
  • Pheniramine
  • Pyridine, 2-(alpha-(2-(dimethylamino)ethyl)benzyl)-

Registry Numbers

CAS Registry Number

  • 86-21-5

FDA UNII

  • 134FM9ZZ6M

Related Registry Number

  • 132-20-7 (bimaleate)

System Generated Number

  • 0000086215

Structure Descriptors

InChI

1S/C16H20N2/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16/h3-10,12,15H,11,13H2,1-2H3

InChIKey

IJHNSHDBIRRJRN-UHFFFAOYSA-N

Smiles

c1([C@@H](c2ccccn2)CCN(C)C)ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 48mg/kg (48mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 211, Pg. 328, 1950.
rabbit LDLo intravenous 30mg/kg (30mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 211, Pg. 328, 1950.
rabbit LDLo intravenous 30mg/kg (30mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

ENDOCRINE: HYPERGLYCEMIA
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 211, Pg. 328, 1950.
women TDLo oral 14mg/kg (14mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
Medical Journal of Australia. Vol. 2, Pg. 110, 1976.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 3.170 (none)   EST
Atmospheric OH Rate Constant 8.85E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.