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Substance Name: Aflibercept [USAN:INN]
RN: 862111-32-8
UNII: 15C2VL427D

Note

  • Has antiangiogenic activity; consists of the second and third Ig domains of VEGFR1 and VEGFR2, respectively, fusion to the Fc region of IgG1; putative antineoplastic agent that binds all VEGF-A isoforms; possible medicine for eye disorders.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Angiogenesis Inhibitor for Treatment of Cancer
  • Inhibitor of Aberrant Angiogenesis-Vascular Leak and Inflammation

Names and Synonyms

Name of Substance

  • Aflibercept [USAN:INN]

Synonyms

  • Aflibercept
  • Aflibercept iso-osmotic ophthalmic
  • AVE 0005
  • AVE0005
  • Bay 86-5321
  • Bay86-5321
  • Eylea
  • HSDB 8258
  • UNII-15C2VL427D
  • VEGF Trap
  • VEGF Trap - regeneron
  • VEGF Trap R1R2
  • VEGF Trap-Eye
  • Zaltrap

Registry Numbers

CAS Registry Number

  • 862111-32-8

FDA UNII

  • 15C2VL427D

Other Registry Number

  • 924289-53-2

System Generated Number

  • 0862111328