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Substance Name: Amolimogene bepiplasmid [USAN:INN]
RN: 870524-46-2


  • A DNA-based therapeutic encoding the E6 and E7 epitopes from HPV; a potential therapy for HPV-associated diseases, including cervical dysplasia; in phase II clinical trial 12/2008.
  • Contains plasmid-DNA-encoding fragments derived from the E6 and E7 proteins of human papillomavirus (HPV) 16 and 18, and is formulated within small biodegradable microparticles; for treatment of high-grade cervical intraepithelial neoplasia, in a randomized controlled trial (2/2004).

Classification Code

  • Treatment of HPV-Mediated Disease
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Links to Resources

Names and Synonyms

Name of Substance

  • Amolimogene bepiplasmid [USAN:INN]


  • Amolimogene bepiplasmid
  • Bacterially derived DNA and microparticles made of poly(D,L-lactide-co- glydolide)
  • ZYC101a

Systematic Name

  • DNA (synthetic plasmid p3kDRalphaHPV16-18)

Registry Numbers

CAS Registry Number

  • 870524-46-2

System Generated Number

  • 0870524462