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Substance Name: Quinagolide [INN:BAN]
RN: 87056-78-8
UNII: 80Q9QWN15M
InChIKey: GDFGTRDCCWFXTG-SCTDSRPQSA-N

Note

  • A non-ergot dopamine D(2)-agonist.

Molecular Formula

  • C20-H33-N3-O3-S

Molecular Weight

  • 395.5647
 

Classification Codes

  • Dopamine Agents
  • Dopamine Agonists
  • Human Data
  • Neurotransmitter Agents
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Quinagolide
  • Quinagolide [INN:BAN]

Synonyms

  • (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
  • BRN 6074559
  • CV 205-502
  • CV205-502
  • Norprolac
  • Quinagolida
  • Quinagolida [INN-Spanish]
  • Quinagolide
  • Quinagolidum
  • Quinagolidum [INN-Latin]
  • SDZ 205-502
  • UNII-80Q9QWN15M

Systematic Names

  • (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
  • Sulfamide, N,N-diethyl-N-(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)-, (3-alpha,4a-alpha,10a-beta)-(+-)-

Registry Numbers

CAS Registry Number

  • 87056-78-8

FDA UNII

  • 80Q9QWN15M

Other Registry Number

  • 132014-58-5

System Generated Number

  • 0087056788

Structure Descriptors

InChI

1S/C20H33N3O3S/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3/t16-,17+,19-/m0/s1

InChIKey

GDFGTRDCCWFXTG-SCTDSRPQSA-N

Smiles

CCCN1C[C@@H](C[C@H]2Cc3c(O)cccc3C[C@H]12)NS(=O)(=O)N(CC)CC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 32ug/kg (0.032mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: EXCITEMENT
Clinical Endocrinology Vol. 40, Pg. 551, 1994.