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Substance Name: Teplizumab [USAN:INN]
RN: 876387-05-2
UNII: S4M959U2IJ

Note

  • A humanized anti-CD3 monoclonal antibody that has been mutated to reduce Fc receptor and complemente binding, used in treatment of type I diabetes.

Molecular Formula

  • C6462-H9938-N1738-O2022-S46
 

Classification Code

  • Type 1 Diabetes
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Links to Resources

Names and Synonyms

Name of Substance

  • Teplizumab [USAN:INN]

Synonyms

  • MGA031
  • Teplizumab
  • UNII-S4M959U2IJ

Systematic Name

  • Immunoglobulin G1, anti-(human CD3 (antigen) ?-chain) (human-mouse monoclonal MGA031 heavy chain), disulfide with human-mouse monoclonal MGA031 light-chain, dimer

Registry Numbers

CAS Registry Number

  • 876387-05-2

FDA UNII

  • S4M959U2IJ

System Generated Number

  • 0876387052