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Substance Name: Acrivastine [USAN:INN:BAN]
RN: 87848-99-5
UNII: A20F9XAI7W
InChIKey: PWACSDKDOHSSQD-IUTFFREVSA-N

Note

  • A second generation antihistamine.

Molecular Formula

  • C22-H24-N2-O2

Molecular Weight

  • 348.444
 

Classification Codes

  • Antihistaminic
  • Histamine Agents
  • Histamine Antagonists
  • Histamine H1 Antagonists
  • Histamine H1 Antagonists, Non-Sedating
  • Neurotransmitter Agents
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Names and Synonyms

Name of Substance

  • Acrivastine
  • Acrivastine [USAN:INN:BAN]

Synonyms

  • (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid
  • (E)-6-((E)-3-(1-Pyrrolidinyl-1-p-tolylpropenyl)-2-pyridinacrylsaeure
  • 2-Propenoic acid, 3-(6-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-2-pyridinyl)-, (E,E)-
  • Acrivastin
  • Acrivastina
  • Acrivastina [Spanish]
  • Acrivastine
  • Acrivastinum
  • Acrivastinum [Latin]
  • BW 825C
  • BW A825C
  • Semprex
  • UNII-A20F9XAI7W

Systematic Name

  • 2-Propenoic acid, 3-(6-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-2-pyridinyl)-, (E,E)-

Mixture Name

  • Semprex-D

Registry Numbers

CAS Registry Number

  • 87848-99-5

FDA UNII

  • A20F9XAI7W

System Generated Number

  • 0087848995

Structure Descriptors

InChI

InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+

InChIKey

PWACSDKDOHSSQD-IUTFFREVSA-N

Smiles

Cc1ccc(cc1)\C(=C/CN2CCCC2)\c3cccc(\C=C\C(=O)O)n3

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 222 dec deg C   EXP
log P (octanol-water) 2.830 (none)   EST
Atmospheric OH Rate Constant 1.73E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.