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Substance Name: Trinitrophenol [NF]
RN: 88-89-1
UNII: A49OS0F91S
InChIKey: OXNIZHLAWKMVMX-UHFFFAOYSA-N

Note

  • Used as antiseptic, astringent & stimulant for epitheliazation.

Molecular Formula

  • C6-H3-N3-O7

Molecular Weight

  • 229.1037
 

Classification Codes

Classification Codes

  • Enzyme Inhibitors
  • Indicators and Reagents
  • Mutation Data
  • Uncoupling Agents

Superlist Classification Codes

  • TWA 0.1 mg/m3
  • TWA 0.1 mg/m3; skin

Names and Synonyms

Name of Substance

  • Picric acid
  • Trinitrophenol [NF]

Synonyms

  • 1,3,5-Trinitrophenol
  • 2,4,6-Trinitrofenol
  • 2,4,6-Trinitrofenol [Dutch]
  • 2,4,6-Trinitrofenolo
  • 2,4,6-Trinitrofenolo [Italian]
  • 2,4,6-Trinitrophenol
  • 2-Hydroxy-1,3,5-trinitrobenzene
  • Acide picrique
  • Acide picrique [French]
  • Acido picrico
  • Acido picrico [Italian]
  • Acidum picrinicum
  • AI3-15403
  • C.I. 10305
  • Carbazotic acid
  • CCRIS 3106
  • CI 10305
  • EINECS 201-865-9
  • HSDB 2040
  • Kyselina pikrova
  • Kyselina pikrova [Czech]
  • Melinite
  • Nitroxanthic acid
  • NSC 36947
  • Phenol trinitrate
  • Phenoltrinitrate
  • Picral
  • Picric acid
  • Picricum acidum
  • Picronitric acid
  • Pikrinezuur
  • Pikrinezuur [Dutch]
  • Pikrinsaeure
  • Pikrinsaeure [German]
  • Pikrynowy kwas
  • Pikrynowy kwas [Polish]
  • Trinitrophenol
  • UNII-A49OS0F91S

Systematic Names

  • 2,4,6-Trinitrophenol
  • Phenol, 2,4,6-trinitro-
  • Picric acid

Superlist Names

  • 2,4,6-Trinitrophenol
  • 2,4,6-Trinitrophenyl
  • NA1344
  • Phenol, 2,4,6-trinitro-
  • Picric acid
  • Picric acid, dry or wetted with < 30% water, by mass
  • Picric acid, wet, with not <10% water
  • Picric acid, wet, with not <10% water [NA1344] [Flammable solid]
  • Trinitrophenol or picric acid, dry or wetted with <30% water, by mass
  • Trinitrophenol or picric acid, dry or wetted with <30% water, by mass [UN0154] [Explosive 1.1D]
  • Trinitrophenol, dry or wetted with < 30% water, by mass
  • Trinitrophenol, wetted with not <30% water, by mass
  • Trinitrophenol, wetted with not <30% water, by mass [UN1344] [Flammable solid]
  • UN0154
  • UN1344

Registry Numbers

CAS Registry Number

  • 88-89-1

FDA UNII

  • A49OS0F91S

Other Registry Numbers

  • 189195-39-9
  • 190402-10-9
  • 29663-11-4
  • 856615-63-9
  • 856993-13-0
  • 857370-42-4

Related Registry Numbers

  • 131-74-8 (ammonium salt)
  • 3324-58-1 (hydrochloride salt)
  • 573-83-1 (potassium salt)
  • 6477-64-1 (lead(2+) salt)

System Generated Number

  • 0000088891

Structure Descriptors

InChI

InChI=1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H

InChIKey

OXNIZHLAWKMVMX-UHFFFAOYSA-N

Smiles

Oc1c(cc(cc1[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 250mg/kg (250mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
dog LDLo subcutaneous 60mg/kg (60mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
dog LDLo unreported 60mg/kg (60mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

CARDIAC: PULSE RATE 		U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 151, 1941.
guinea pig LDLo oral 100mg/kg (100mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
mouse LD50 intraperitoneal 56300ug/kg (56.3mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56, Pg. 450, 1960.
pigeon LDLo subcutaneous 200mg/kg (200mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rabbit LDLo oral 120mg/kg (120mg/kg)   U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 151, 1941.
rabbit LDLo oral 120mg/kg (120mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 151, 1941.
rat LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: TREMOR

SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Journal of Toxicology and Environmental Health. Vol. 37, Pg. 313, 1992.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 122.5 deg C   EXP
pKa Dissociation Constant 0.38 (none) 25 EXP
log P (octanol-water) 1.33 (none)   EXP
Water Solubility 1.27E+04 mg/L 25 EXP
Vapor Pressure 7.50E-07 mm Hg 25 EXP
Henry's Law Constant 1.70E-11 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.41E-13 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.