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Substance Name: Cefepime [USAN:INN:BAN]
RN: 88040-23-7
UNII: 807PW4VQE3
InChIKey: HVFLCNVBZFFHBT-ZKDACBOMSA-N

Note

  • A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.

Molecular Formula

  • C19-H24-N6-O5-S2

Molecular Weight

  • 480.5676
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterial

Names and Synonyms

Name of Substance

  • Cefepime
  • Cefepime [USAN:INN:BAN]

MeSH Heading

  • Cefepime

Synonyms

  • 1-(((6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methylpyrrolidinium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime)
  • BMY 28142
  • BMY-28142
  • Cefepima
  • Cefepima [Spanish]
  • Cefepime
  • Cefepimum
  • Cefepimum [Latin]
  • Maxipime
  • Pyrrolidinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methyl-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-
  • UNII-807PW4VQE3

Systematic Name

  • Pyrrolidinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methyl-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-

Registry Numbers

CAS Registry Number

  • 88040-23-7

FDA UNII

  • 807PW4VQE3

Other Registry Number

  • 107648-84-0

System Generated Number

  • 0088040237

Structure Descriptors

InChI

InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12-/t13-,17-/m1/s1

InChIKey

HVFLCNVBZFFHBT-ZKDACBOMSA-N

Smiles

CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)[O-])C[N+]3(C)CCCC3)\c4csc(N)n4