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Substance Name: Amlodipine maleate [USAN]
RN: 88150-47-4
UNII: CQ27G2BZJM
InChIKey: TZNOWAJJWCGILX-BTJKTKAUSA-N

Note

  • A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of angina pectoris and hypertension.

Molecular Formula

  • C20-H25-Cl-N2-O5.C4-H4-O4

Molecular Weight

  • 524.951
 

Classification Codes

  • Anti-Anginal
  • Antihypertensive
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Names and Synonyms

Name of Substance

  • Amlodipine maleate [USAN]

Synonyms

  • 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (+-)-, (Z)-2-butenedioate (1:1)
  • 3-Ethyl 5-methyl (+-)-2-((2-aminoethoxy)methyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, maleate (1:1)
  • Amlodipine (+-)-form maleate
  • Amlodipine maleate
  • Amvaz
  • UK 48,340-11
  • UK-48,340-11
  • UNII-CQ27G2BZJM

Systematic Name

  • 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (+-)-, (Z)-2-butenedioate (1:1)

Registry Numbers

CAS Registry Number

  • 88150-47-4

FDA UNII

  • CQ27G2BZJM

Related Registry Number

  • 88150-42-9 (Parent)

System Generated Number

  • 0088150474

Molecular Formulas

Molecular Formula

  • C20-H25-Cl-N2-O5.C4-H4-O4

Molecular Formula Fragments

  • C20-H25-Cl-N2-O5
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChIKey

TZNOWAJJWCGILX-BTJKTKAUSA-N

Smiles

CCOC(=O)C1=C(COCCN)NC(=C(C1c2ccccc2Cl)C(=O)OC)C.OC(=O)\C=C/C(=O)O