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Substance Name: Fosinopril sodium [USAN:USP]
RN: 88889-14-9
UNII: NW2RTH6T2N
InChIKey: CRWFDMPJGMUBGF-WATAJHSMSA-M

Note

  • A phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.

Molecular Formula

  • C30-H45-N-Na-O7-P

Molecular Weight

  • 585.6495
 

Classification Codes

  • Antihypertensive
  • Enzyme Inhibitor (Angiotensin-Converting)
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Names and Synonyms

Name of Substance

  • Fosinopril sodium [USAN:USP]

Synonyms

  • (4S)-4-Cyclohexyl-1-(((R)-((S)-1-hydroxy-2-methylpropoxy)(4-phenylbutyl)phosphinyl)acetyl-L-proline propionate (ester), sodium salt
  • Acecor
  • Acenor-M
  • Dynacil
  • Eliten
  • Eosinopril
  • Fosinil
  • Fosinopril sodium
  • Fosinorm
  • Fosipres
  • Fositen
  • Fositens
  • Foziretic
  • Fucithalmic
  • Hiperlex
  • L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, sodium salt, (1(S*(R*)),2alpha,4beta)-
  • Monopril
  • Newace
  • Sapril
  • SQ 28555
  • Staril
  • Tenso Stop
  • Tensogard
  • UNII-NW2RTH6T2N

Systematic Name

  • L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, sodium salt, (1(S*(R*)),2alpha,4beta)-

Superlist Name

  • SQ 28555

Registry Numbers

CAS Registry Number

  • 88889-14-9

FDA UNII

  • NW2RTH6T2N

System Generated Number

  • 0088889149

Structure Descriptors

InChI

InChI=1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+2/p-1/t25-,26+,30+,39-;/m1./s1

InChIKey

CRWFDMPJGMUBGF-WATAJHSMSA-M

Smiles

[Na+2].CCC(=O)O[C@@H](O[P@](=O)(CCCCc1ccccc1)CC(=O)N2C[C@@H](C[C@H]2C(=O)[O-])C3CCCCC3)C(C)C