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Substance Name: Tutocaine
RN: 891-33-8
UNII: P1B8E343GD
InChIKey: MTNXJJYHFCSXCP-UHFFFAOYSA-N

Molecular Formula

  • C14-H22-N2-O2

Molecular Weight

  • 250.3398
 
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Names and Synonyms

Results Name

  • Tutocaine

Name of Substance

  • Tutocaine

Synonyms

  • 4-(Dimethylamino)-3-methyl-2-butanol p-aminobenzoate (ester)
  • 4-14-00-01142 (Beilstein Handbook Reference)
  • BRN 2731344
  • EINECS 212-966-2
  • Tutocaine
  • UNII-P1B8E343GD

Systematic Names

  • 2-Butanol, 4-(dimethylamino)-3-methyl-, 4-aminobenzoate (ester)
  • 2-Butanol, 4-(dimethylamino)-3-methyl-, p-aminobenzoate (ester)
  • 3-(Dimethylamino)-1,2-dimethylpropyl p-aminobenzoate

Registry Numbers

CAS Registry Number

  • 891-33-8

FDA UNII

  • P1B8E343GD

Other Registry Number

  • 25318-28-9

System Generated Number

  • 0000891338

Structure Descriptors

InChI

1S/C14H22N2O2/c1-10(9-16(3)4)11(2)18-14(17)12-5-7-13(15)8-6-12/h5-8,10-11H,9,15H2,1-4H3

InChIKey

MTNXJJYHFCSXCP-UHFFFAOYSA-N

Smiles

CC(CN(C)C)C(C)OC(=O)c1ccc(cc1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intraperitoneal 80mg/kg (80mg/kg) BEHAVIORAL: GENERAL ANESTHETIC "Nachprufung der Toxicitat von Novocain und Tutocain bei Chloralisierten Tieren, Dissertation," Barke, A., Pharmakologischen Institut der Tierarztlichen Hochschule zu Hannover, Fed. Rep. Ger., 1936Vol. -, Pg. -, 1936.
dog LDLo intravenous 15mg/kg (15mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
frog LDLo intraspinal 200mg/kg (200mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 45, Pg. 291, 1932.
guinea pig LDLo intraperitoneal 250mg/kg (250mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo intravenous 30mg/kg (30mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo subcutaneous 193mg/kg (193mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LDLo intravenous 50mg/kg (50mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LDLo subcutaneous 350mg/kg (350mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
rabbit LDLo intraspinal 15600ug/kg (15.6mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 137, 1935.
rabbit LDLo intravenous 15mg/kg (15mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
rabbit LDLo subcutaneous 200mg/kg (200mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
rat LDLo intravenous 180mg/kg (180mg/kg)   "Die Krampfmischung der Lokalanaesthetica, ihre Beeinflussung durch Mineralsalze und Adrenalin, Dissertation," Hoppe, G., Pharmakologischen Institut der Albertus-Universitat zu Konigsberg Pr., Germany, 1933.Vol. -, Pg. -, 1933.