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Substance Name: Etaracizumab [USAN:INN]
RN: 892553-42-3
UNII: 41W9MFI160


  • Humanized version of LM609; potential antiangiogenic agent.

Molecular Formula

  • C6392-H9908-N1732-O1996-S42

Classification Codes

  • Treatment of Metastatic Melanoma
  • Treatment of Metastatic Melanoma, Prostate Cancer
  • Treatment of Prostate Cancer
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Links to Resources

Names and Synonyms

Name of Substance

  • Etaracizumab
  • Etaracizumab [USAN:INN]


  • A fully humanized, recombinant IgG kappa monoclonal antibody
  • Abegrin
  • Etaracizumab
  • Immunoglobulin G1, anti-(human alphaVbeta3 (CD51/CD61, CD51/GPIIIa, CD51/platelet membrane glycoprotein IIIa, vitronectin receptor)) humanized monoclonal antibody MEDI-522 (hLM609); gamma1 heavy chain (humanized VH (Homo sapiens FR/Mus musculus CDR from clone LM609)-Homo sapiens IGHG1*03) (220-214')-disulfide with kappa light chain (humanized V-KAPPA (Homo sapiens FR/Mus musculus CDR from clone LM609)-Homo sapiens IGKC*01); (226-226'':229-229'')-bisdisulfide dimer
  • LM 609
  • UNII-41W9MFI160
  • Vitaxin

Systematic Name

  • Immunoglobulin G1 (synthetic mouse NSO cell heavy chain variable region fragment), complex with immunoglobulin G1 (synthetic mouse NSO cell light chain variable region fragment)

Registry Numbers

CAS Registry Number

  • 892553-42-3


  • 41W9MFI160

Other Registry Number

  • 324740-00-3

System Generated Number

  • 0892553423