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Substance Name: Tropisetron [INN:BAN]
RN: 89565-68-4
UNII: 6I819NIK1W
InChIKey: ZNRGQMMCGHDTEI-ITGUQSILSA-N

Classification Codes

  • Antiemetics
  • Autonomic Agents
  • Central Nervous System Agents
  • Gastrointestinal Agents
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Serotonin Agents
  • Serotonin Antagonists

Molecular Formula

  • C17-H20-N2-O2

Molecular Weight

  • 284.357
 
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Names and Synonyms

Name of Substance

  • Tropisetron
  • Tropisetron [INN:BAN]
  • Tropisteron

Synonyms

  • ICF 205-930
  • ICS 205930
  • Tropisetron
  • Tropisetronum
  • Tropisetronum [INN-Latin]
  • UNII-6I819NIK1W

Systematic Names

  • 1alphaH,5alphaH-Tropan-3alpha-yl indole-3-carboxylate
  • 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-

Registry Numbers

CAS Registry Number

  • 89565-68-4

FDA UNII

  • 6I819NIK1W

System Generated Number

  • 0089565684

Structure Descriptors

InChI

1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+

InChIKey

ZNRGQMMCGHDTEI-ITGUQSILSA-N

Smiles

CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)c3c[nH]c4ccccc34

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo intravenous 800ug/kg/2D-I (0.8mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Lancet. Vol. 1, Pg. 1494, 1987.