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Substance Name: Pyruvate decarboxylase
RN: 9001-04-1


  • Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC
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Names and Synonyms

Name of Substance

  • Pyruvate decarboxylase

MeSH Heading

  • Pyruvate Decarboxylase


  • alpha-Carboxylase
  • alpha-Keto acid decarboxylas
  • alpha-Ketoisovalerate decarboxylase
  • E.C.
  • Pyruvic Decarboxylase

Registry Numbers

CAS Registry Number

  • 9001-04-1

Other Registry Numbers

  • 9024-95-7
  • 9031-03-2

System Generated Number

  • 0009001041