Substance Name: Factor IX Complex
RN: 9001-28-9
Note
- Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
Molecular Formula
- Unspecified
Classification Code
- Drug / Therapeutic Agent
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Names and Synonyms
Name of Substance
- Factor IX
- Factor IX Complex
MeSH Heading
- Factor IX
Synonyms
- AHF-B
- AlphaNine SD
- Antihemophilic factor B
- Bebulin VH
- Bemofil
- Blood-plasma thromboplastin component
- Blutgerinnungsfaktor IX
- Christmas factor
- Coagulation factor IX
- Coagulation factor IX human
- EINECS 232-594-4
- Factor IX
- Factor IX Complex
- FIX-HP/SD
- Immunine
- Monofix-VF
- Mononine
- Nanotiv
- Nonafact
- Octanine
- Plasma thromboplastin component
- PTC
- PTC (blood coagulation factor)
- Replenine
- Rixubis
Systematic Names
- Blood coagulation factor IX
- Blood-coagulation factor IX
Registry Numbers
CAS Registry Number
- 9001-28-9
Other Registry Number
- 9035-63-6
System Generated Number
- 0009001289
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 1000ug/kg (1mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BLOOD: HEMORRHAGE LIVER: OTHER CHANGES | Developments in Biological Standardization. Vol. 44, Pg. 185, 1979. |