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Substance Name: Factor IX Complex
RN: 9001-28-9

Note

  • Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).

Molecular Formula

  • Unspecified
 

Classification Code

  • Drug / Therapeutic Agent

Names and Synonyms

Name of Substance

  • Factor IX
  • Factor IX Complex

MeSH Heading

  • Factor IX

Synonyms

  • AHF-B
  • AlphaNine SD
  • Antihemophilic factor B
  • Bebulin VH
  • Bemofil
  • Blood-plasma thromboplastin component
  • Blutgerinnungsfaktor IX
  • Christmas factor
  • Coagulation factor IX
  • Coagulation factor IX human
  • EINECS 232-594-4
  • Factor IX
  • Factor IX Complex
  • FIX-HP/SD
  • Immunine
  • Monofix-VF
  • Mononine
  • Nanotiv
  • Nonafact
  • Octanine
  • Plasma thromboplastin component
  • PTC
  • PTC (blood coagulation factor)
  • Replenine
  • Rixubis

Systematic Names

  • Blood coagulation factor IX
  • Blood-coagulation factor IX

Registry Numbers

CAS Registry Number

  • 9001-28-9

Other Registry Number

  • 9035-63-6

System Generated Number

  • 0009001289

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1000ug/kg (1mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BLOOD: HEMORRHAGE

LIVER: OTHER CHANGES
Developments in Biological Standardization. Vol. 44, Pg. 185, 1979.