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Substance Name: Leucyl aminopeptidase
RN: 9001-61-0


  • A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.

Molecular Formula

  • Unspecified

Classification Code

  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Names and Synonyms

MeSH Heading

  • Leucyl Aminopeptidase


  • EINECS 232-618-3
  • Leucine aminopeptidase

Systematic Names

  • Aminopeptidase, cytosol
  • Aminopeptidase, leucyl
  • Leucyl aminopeptidase

Registry Numbers

CAS Registry Number

  • 9001-61-0

Other Registry Numbers

  • 9027-20-7
  • 9054-62-0

System Generated Number

  • 0009001610