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Substance Name: Phosphofructokinase
RN: 9001-80-3


  • An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.

Molecular Formula

  • Unspecified

Classification Code

  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Names and Synonyms

MeSH Heading

  • Phosphofructokinase-1


  • E.C.
  • EINECS 232-633-5

Systematic Names

  • Kinase (phosphorylating), phosphofructo-
  • Phosphofructokinase

Registry Numbers

CAS Registry Number

  • 9001-80-3

System Generated Number

  • 0009001803