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Substance Name: Trypsin [INN:BAN:JAN]
RN: 9002-07-7
UNII: GV54A213NN

Note

  • From bovine pancreas.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Natural Product
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)

Names and Synonyms

Name of Substance

  • Trypsin
  • Trypsin [INN:BAN:JAN]
  • Trypsin, pancreatic, type V-S

MeSH Heading

  • Trypsin

Synonyms

  • CCRIS 7094
  • Cocoonase
  • EC 3.4.21.4
  • EC 3.4.4.4
  • EINECS 232-650-8
  • Enzyme, tryptic
  • HSDB 3409
  • Parenzyme
  • Parenzymol
  • Pseudotrypsin
  • Trypsin
  • Tryptar
  • Tryptase
  • Trypure
  • U-4858
  • UNII-GV54A213NN
  • Vasolex

Systematic Name

  • Trypsin

Superlist Name

  • Trypsin

Mixture Names

  • Optase
  • Trypsin complex

Registry Numbers

CAS Registry Number

  • 9002-07-7

FDA UNII

  • GV54A213NN

Other Registry Numbers

  • 146990-35-4
  • 213972-07-7
  • 214265-38-0
  • 9068-82-0

System Generated Number

  • 0009002077

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 30000units/kg (30000units/kg) BLOOD: OTHER CHANGES

BEHAVIORAL: GENERAL ANESTHETIC

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 164, 1956.
mouse LD50 intramuscular 105mg/kg (105mg/kg)   Drugs in Japan Vol. -, Pg. 744, 1990.
mouse LD50 intraperitoneal 100mg/kg (100mg/kg)   Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982.
mouse LD50 intravenous 11100ug/kg (11.1mg/kg)   Drugs in Japan Vol. 6, Pg. 523, 1982.
mouse LD50 oral 1450mg/kg (1450mg/kg)   Drugs in Japan Vol. -, Pg. 744, 1990.
rabbit LD50 intravenous 2200ug/kg (2.2mg/kg)   Drugs in Japan Vol. 6, Pg. 523, 1982.
rat LD50 intramuscular 200mg/kg (200mg/kg)   Drugs in Japan Vol. -, Pg. 744, 1990.
rat LD50 intraperitoneal > 51mg/kg (51mg/kg)   Drugs in Japan Vol. -, Pg. 744, 1990.
rat LD50 intravenous 36mg/kg (36mg/kg)   Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 744, 1990.