Substance Name: Trypsin [INN:BAN:JAN]
RN: 9002-07-7
UNII: GV54A213NN
Note
- From bovine pancreas.
Molecular Formula
- Unspecified
Classification Codes
- Drug / Therapeutic Agent
- Mutation Data
- Natural Product
- TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Trypsin
- Trypsin [INN:BAN:JAN]
- Trypsin, pancreatic, type V-S
MeSH Heading
- Trypsin
Synonyms
- Acetyltrypsin
- CCRIS 7094
- Cocoonase
- EC 3.4.21.4
- EC 3.4.4.4
- EINECS 232-650-8
- Enzyme, tryptic
- HSDB 3409
- Parenzyme
- Parenzymol
- Pseudotrypsin
- Trypsin
- Tryptar
- Tryptase
- Trypure
- U-4858
- UNII-GV54A213NN
- Vasolex
Systematic Name
- Trypsin
Superlist Name
- Trypsin
Mixture Names
- Optase
- Trypsin complex
Registry Numbers
CAS Registry Number
- 9002-07-7
FDA UNII
- GV54A213NN
Other Registry Numbers
- 146990-35-4
- 213972-07-7
- 214265-38-0
- 9068-82-0
System Generated Number
- 0009002077
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LDLo | intravenous | 30000units/kg (30000units/kg) | BLOOD: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 164, 1956. |
| mouse | LD50 | intramuscular | 105mg/kg (105mg/kg) | Drugs in Japan Vol. -, Pg. 744, 1990. | |
| mouse | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982. | |
| mouse | LD50 | intravenous | 11100ug/kg (11.1mg/kg) | Drugs in Japan Vol. 6, Pg. 523, 1982. | |
| mouse | LD50 | oral | 1450mg/kg (1450mg/kg) | Drugs in Japan Vol. -, Pg. 744, 1990. | |
| rabbit | LD50 | intravenous | 2200ug/kg (2.2mg/kg) | Drugs in Japan Vol. 6, Pg. 523, 1982. | |
| rat | LD50 | intramuscular | 200mg/kg (200mg/kg) | Drugs in Japan Vol. -, Pg. 744, 1990. | |
| rat | LD50 | intraperitoneal | > 51mg/kg (51mg/kg) | Drugs in Japan Vol. -, Pg. 744, 1990. | |
| rat | LD50 | intravenous | 36mg/kg (36mg/kg) | Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982. | |
| rat | LD50 | oral | > 5gm/kg (5000mg/kg) | Drugs in Japan Vol. -, Pg. 744, 1990. |