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Substance Name: Corticotropin [USP:INN:BAN]
RN: 9002-60-2

Note

  • An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

Molecular Formula

  • Unspecified
 

Classification Codes

  • Diagnostic Aid (Adrenocortical Insufficiency)
  • Glucocorticoid
  • Hormone (Adrenocorticotropic)
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Human Data
  • Natural Product
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Corticotropin
  • Corticotropin [USP:INN:BAN]

MeSH Heading

  • Adrenocorticotropic hormone

Synonyms

  • Acethropan
  • Acortan
  • Acorto
  • ACTH
  • Acthar
  • Acton
  • Actonar
  • Adrenal cortex hormone
  • Adrenocorticotrophic hormone
  • Adrenocorticotrophin
  • Adrenocorticotropic hormone
  • Adrenocorticotropin
  • Adrenomone
  • Adrenotrophin
  • Alfatrofin
  • CCRIS 6752
  • Cibacthen
  • Corstiline
  • Corticotrofina
  • Corticotrofina [INN-Spanish]
  • Corticotrophin
  • Corticotrophine
  • Corticotrophine [INN-French]
  • Corticotrophinum
  • Corticotrophinum [INN-Latin]
  • Corticotropin
  • Corticotropin, repository
  • Corticotropin-like substances
  • Corticotropina
  • Corticotropina [DCIT]
  • Corticotropine
  • Corticotropinum
  • Cortigel
  • Cortiphyson
  • Cortrophin
  • Depo-Acth
  • Duracton
  • Dynamone
  • EINECS 232-659-7
  • Exacthin
  • HSDB 7773
  • Humactid
  • Isactid
  • Nuvacthen
  • Pituitary gland adreno cortico-tropic hormone
  • ProActon
  • Purified Cortrophin gel
  • Reacthin
  • Solacthyl
  • Tubex

Systematic Names

  • Adrenocorticotropin
  • Corticotropin

Registry Numbers

CAS Registry Number

  • 9002-60-2

Other Registry Numbers

  • 55127-96-3
  • 8049-37-4
  • 8049-43-2
  • 8049-68-1
  • 8049-86-3
  • 8049-87-4
  • 9006-61-5
  • 9040-10-2

System Generated Number

  • 0009002602

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
infant TDLo unreported 240mg/kg/16W- (240mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES Lancet. Vol. 1, Pg. 901, 1984.