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Substance Name: Melanocyte-Stimulating Hormones
RN: 9002-79-3


  • Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS OF HYPOTHALAMUS.

Molecular Formula

  • Unspecified

Classification Codes

  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
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Names and Synonyms

Name of Substance

  • Melanocyte-Stimulating Hormones

MeSH Heading

  • Melanocyte-Stimulating Hormones


  • Melanophore hormone
  • Melanophore-expanding hormone
  • Melanophore-stimulating hormone
  • MSH
  • Pigment hormone

Systematic Names

  • Active principle of the pars intermedia of the pituitary
  • Mel-stimulating hormone
  • Melanotropin

Registry Numbers

CAS Registry Number

  • 9002-79-3

Other Registry Number

  • 879549-37-8

System Generated Number

  • 0009002793