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Substance Name: Dodecyl alcohol, ethoxylated
RN: 9002-92-0

Note

  • Polyethylene glycol monododecyl ether (average polymer n=9).

Molecular Formula

  • (C2-H4-O)mult-C12-H26-O

Molecular Weight

  • 230.389
 

Classification Codes

  • Cardiovascular Agents
  • Detergents
  • Mutation Data
  • Pharmaceutic Aid (Surfactant)
  • Pharmaceutical Solutions
  • Sclerosing Solutions
  • Skin / Eye Irritant
  • Spermaticide
  • Surface-Active Agents
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Links to Resources

Names and Synonyms

Results Name

  • Dodecyl alcohol, ethoxylated

Name of Substance

  • 3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol
  • Dodecyl alcohol, ethoxylated
  • Laureth 4 [USAN]
  • Laureth 9 [USAN]
  • Laureth-11
  • Lauromacrogol 400 [INN]
  • PEG-11 Lauryl ether
  • Polidocanol

Synonyms

  • 40L (polyether)
  • Actinol L 7
  • Actinol L3
  • Adeka Carpol M 2
  • Adeka Carpol MBF 100
  • Adekatol LA 1275
  • Aethoxysklerol
  • Aetoxisclerol
  • Akyporox RLM 160
  • Akyporox RLM 22
  • Akyporox RLM 230
  • Akyporox RLM 40
  • Aldosperse L 9
  • Alkasurf LAN 1
  • Alkasurf LAN 3
  • alpha-Dodecyl-omega-hydroxypoly(oxy-1,2-ethanediyl)
  • alpha-Dodecyl-omega-hydroxypoly(oxyethylene)
  • Arapol 0712
  • Atlas G 2133
  • Atlas G 3705
  • Atlas G 3707
  • Atlas G 4829
  • Atlas G-2133
  • Atlas G-3705
  • Atossisclerol
  • B 205
  • Base LP 12
  • BL 9
  • BL 9 (polyglycol)
  • Brij 22
  • Brij 23
  • Brij 30
  • Brij 30ICI
  • Brij 30SP
  • Brij 35
  • Brij 35L
  • Brij 36T
  • Calgene 40L
  • Carsonol L 2
  • Carsonol L 3
  • CCRIS 3397
  • Chemal LA 23
  • Chimipal AE 3
  • Cimagel
  • Conion 275-100
  • Conion 275-20
  • Conion 275-30
  • Conion 275-80
  • Conion 2P80
  • Dodecanol, ethoxylate
  • Dodecyl alcohol polyoxyethylene ether
  • Du Pont WK
  • EC 500-002-6
  • Ethosperse LA 12
  • Ethosperse LA 23
  • Ethoxylated lauryl alcohol
  • Ethoxysclerol
  • G 3707
  • Glycols, polyethylene, monododecyl ether
  • HSDB 4351
  • Hydroxypolyethoxydodecane
  • LA (Alcohol)
  • LA 7
  • Laureth
  • Laureth 4
  • Laureth 9
  • Lauromacrogol
  • Lauromacrogol 400
  • Lipal 4LA
  • Lubrol 12A9
  • Lubrol PX
  • Marlipal 1217
  • Mergital LM 11
  • NCI-C54875
  • Newcol 1203
  • Nikkol BL
  • Noigen ET 160
  • Noigen ET 170
  • Noigen YX 500
  • Nonaethyleneglycol monododecyl ether
  • Noniolite AL 20
  • Pegnol L 12
  • Polidocanol
  • Poly(oxy-1,2-ethanediyl), alpha-dodecyl-omega-hydroxy-
  • Polyethylene glycol monododecyl ether
  • Polyethylene glycol monododecyl ether, the name is followed by a number (400) corresponding approximately to the average molecular mass of the polyethylene glycol portion
  • Polyethylene glycol monolauryl ether
  • Polyoxyethylene 9-lauryl ether
  • Polyoxyethylene lauryl ether
  • Polyoxyethylenedodecyl ether
  • Polyoxyl lauryl ether
  • Rokanol L
  • Romopal LN
  • Simulsol P 23
  • Simulsol P 4
  • Siponic L
  • Slovasol S
  • Standamul LA 2
  • Stmer 135
  • Surfactant WK
  • Texofor B 9
  • Thesat
  • Thesit
  • UNII-002FR4N8OV
  • UNII-0AWH8BFG9A
  • UNII-5Q366RLH25
  • UNII-6HQ855798J
  • UNII-6SU0SC83AH
  • UNII-APG12V4K45
  • UNII-BD7AST04GA
  • UNII-ELB3Y6474W
  • UNII-KZF7XN8153
  • UNII-MGU0HEW21Q
  • UNII-N72LMW566G
  • UNII-OAH19558U1
  • UNII-QU7U88D04I
  • UNII-RPD53041LR
  • UNII-W9D845551A
  • UNII-WG3R46N0SV
  • UNII-Z95S6G8201

Systematic Names

  • A mixture of monolauryl ethers of polyoxyethylene glycols having a statistical average of 8 ethylene oxide groups per molecule
  • alpha-Dodecyl-omega-hydroxypoly(oxy-1,2ethanediyl)
  • Dodecan-1-ol, ethoxylated
  • Glycols, polyethylene, monododecyl ether
  • Polidocanol
  • Poly(oxy-1,2-ethanediyl), alpha-dodecyl-omega-hydroxy-

Superlist Names

  • alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100
  • Ethoxylated lauryl alcohol
  • Polyoxyethylene dodecyl mono ether

Registry Numbers

CAS Registry Number

  • 9002-92-0

FDA UNIIs

  • 002FR4N8OV
  • 0AWH8BFG9A
  • 5Q366RLH25
  • 6HQ855798J
  • 6SU0SC83AH
  • APG12V4K45
  • BD7AST04GA
  • ELB3Y6474W
  • KZF7XN8153
  • MGU0HEW21Q
  • N72LMW566G
  • OAH19558U1
  • QU7U88D04I
  • RPD53041LR
  • W9D845551A
  • WG3R46N0SV
  • Z95S6G8201

Other Registry Numbers

  • 101008-55-3
  • 1010802-24-0
  • 101840-74-8
  • 102329-60-2
  • 102342-03-0
  • 106254-08-4
  • 106254-09-5
  • 106856-65-9
  • 1075258-12-6
  • 1075258-13-7
  • 11106-34-6
  • 113716-35-1
  • 122779-58-2
  • 1231209-22-5
  • 1235485-65-0
  • 124401-71-4
  • 1263057-78-8
  • 12789-47-8
  • 1334-72-1
  • 1338464-84-8
  • 1341-05-5
  • 1361543-25-0
  • 137736-73-3
  • 138100-08-0
  • 141875-75-4
  • 14675-38-8
  • 147398-17-2
  • 148093-10-1
  • 148498-91-3
  • 152206-24-1
  • 176235-62-4
  • 176596-95-5
  • 183117-57-9
  • 186762-97-0
  • 189388-50-9
  • 191546-41-5
  • 201746-17-0
  • 218607-00-2
  • 221642-91-7
  • 234761-81-0
  • 234761-82-1
  • 234761-83-2
  • 234764-37-5
  • 258278-32-9
  • 266678-04-0
  • 266678-05-1
  • 31798-98-8
  • 348616-52-4
  • 359786-16-6
  • 362661-71-0
  • 37231-23-5
  • 37343-87-6
  • 384842-79-9
  • 39316-02-4
  • 39316-41-1
  • 39363-77-4
  • 459409-03-1
  • 503027-85-8
  • 504414-58-8
  • 50815-85-5
  • 50815-86-6
  • 51426-13-2
  • 53026-66-7
  • 53241-34-2
  • 54351-54-1
  • 54398-17-3
  • 55599-84-3
  • 55892-94-9
  • 56093-86-8
  • 56590-57-9
  • 56939-70-9
  • 57244-90-3
  • 61373-94-2
  • 61710-38-1
  • 62229-27-0
  • 64772-19-6
  • 648426-35-1
  • 6540-99-4
  • 66048-74-6
  • 69344-85-0
  • 71636-71-0
  • 71932-08-6
  • 777931-72-3
  • 786657-31-6
  • 798544-27-1
  • 8027-11-0
  • 86547-02-6
  • 86727-31-3
  • 869893-21-0
  • 87296-34-2
  • 875119-83-8
  • 9015-55-8
  • 903524-77-6
  • 9079-21-4
  • 935753-05-2
  • 942439-95-4
  • 942929-81-9
  • 946527-74-8

System Generated Number

  • 0009002920

Molecular Formulas

Molecular Formula

  • (C2-H4-O)mult-C12-H26-O

Molecular Formula Fragments

  • C12-H26-O
  • C2-H4-O
  • COMPONENT

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 38mg/kg (38mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

KIDNEY, URETER, AND BLADDER: HEMATURIA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
guinea pig LD50 oral 384mg/kg (384mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
mouse LD50 intraperitoneal 160mg/kg (160mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
mouse LD50 intraperitoneal 160mg/kg (160mg/kg)   Drugs in Japan Vol. -, Pg. 1300, 1995.
mouse LD50 intravenous 100mg/kg (100mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
mouse LD50 intravenous 100mg/kg (100mg/kg)   Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965.
mouse LD50 oral 1170mg/kg (1170mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
mouse LD50 oral 1170mg/kg (1170mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
mouse LD50 oral 3500mg/kg (3500mg/kg)   American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.
mouse LD50 oral 4940mg/kg (4940mg/kg)   American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.
mouse LD50 subcutaneous 792mg/kg (792mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
mouse LD50 subcutaneous 792300ug/kg (792.3mg/kg)   Drugs in Japan Vol. -, Pg. 1300, 1995.
rabbit LD50 intratracheal > 15mg/kg (15mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.
rabbit LD50 intravenous 36mg/kg (36mg/kg) KIDNEY, URETER, AND BLADDER: HEMATURIA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
rabbit LD50 parenteral > 75mg/kg (75mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.
rat LD50 intraperitoneal 125mg/kg (125mg/kg) GASTROINTESTINAL: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.
rat LD50 intravenous 27mg/kg (27mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
rat LD50 intravenous 27mg/kg (27mg/kg)   Drugs in Japan Vol. -, Pg. 1300, 1995.
rat LD50 intravenous 390mg/kg (390mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
rat LD50 oral 1gm/kg (1000mg/kg) LIVER: FATTY LIVER DEGERATION

GASTROINTESTINAL: OTHER CHANGES

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.
rat LD50 oral 2060mg/kg (2060mg/kg)   "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 300, 1972.
rat LD50 oral 4150mg/kg (4150mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
rat LD50 oral 8600mg/kg (8600mg/kg)   Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.
rat LD50 oral 8600mg/kg (8600mg/kg)   Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.
rat LD50 subcutaneous 953mg/kg (953mg/kg)   Drugs in Japan Vol. -, Pg. 1300, 1995.
rat LD50 subcutaneous 954mg/kg (954mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.