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Substance Name: Povidone [USAN:USP:INN:BAN]
RN: 9003-39-8

Note

  • A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.

Molecular Formula

  • (C6-H9-N-O)x-

Molecular Weight

  • 111.143
 

Classification Codes

Classification Codes

  • Blood Substitutes
  • Diagnostic Aid (Hypoalbuminemia)
  • Hematologic Agents
  • Pharmaceutic Aid (Dispersing and Suspending Agent)
  • Pharmaceutic Aid (Tablet Excipient)
  • Pharmaceutic Aids
  • Plasma Substitutes
  • Radioactive Agent
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
  • Tumor Data

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 3

Names and Synonyms

Name of Substance

  • Crospovidone [INN]
  • Poly(1-vinyl-2-pyrrolidinone)
  • Polyvinylpyrrolidone
  • Povidone
  • Povidone [USAN:USP:INN:BAN]

MeSH Heading

  • Povidone

Synonyms

  • 1-Ethenyl-2-pyrrolidinone homopolymer
  • 1-Ethenyl-2-pyrrolidinone polymers
  • 1-Ethenyl-2-pyrrolidinone, homopolymer
  • 1-Vinyl-2-pyrrolidinone homopolymer
  • 1-Vinyl-2-pyrrolidinone polymer
  • 1-Vinyl-2-pyrrolidone polymer
  • 143 RP
  • 2-Pyrrolidinone, 1-ethenyl, homopolymer
  • 2-Pyrrolidinone, 1-vinyl-, polymers
  • 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with aluminum acetate
  • Agent AT 717
  • Agrimer
  • Albigen A
  • Aldacol Q
  • alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2-oxo-1-pyrrolidinyl)ethylene)-(sup 131)I
  • alpha-Hydro-omega-(p-iodobenzyl)poly(1-(2-oxo-1-pyrrolidinyl)ethylene)-(sup 131)I. (A small part of the iodine is the radioactive isotope, (sup 131)I.)
  • Antaron P 804
  • AT 717
  • Bolinan
  • Caswell No. 681
  • CCRIS 3611
  • Crospovidone
  • Crospovidonum
  • Crospovidonum [INN-Latin]
  • EPA Pesticide Chemical Code 079033
  • Ganex P 804
  • Ganex p-804
  • Hemodesis
  • Hemodez
  • HSDB 205
  • K 115 (polyamide)
  • K 115 (VAN)
  • K 15
  • K 25 (polymer)
  • K 25 (VAN)
  • K 30 (polymer)
  • K 30 (VAN)
  • K 60 (polymer)
  • K 60 (VAN)
  • K 90
  • K115
  • K115 (polyamide)
  • K15
  • K25
  • K25 (polymer)
  • K30
  • K30 (polymer)
  • K60
  • K60 (polymer)
  • K90
  • Kollidin CLM
  • Kollidon
  • Kollidon 17
  • Kollidon 25
  • Kollidon 25, 30, 12PF, 17PF, 90F
  • Kollidon 30
  • Kollidon CL
  • Kollidon CLM
  • Luviskol
  • Luviskol K30
  • Luviskol K90
  • MPK 90
  • N-Vinyl-2-pyrrolidone polymer
  • N-Vinylbutyrolactam polymer
  • N-Vinylpyrrolidinone polymer
  • N-Vinylpyrrolidone polymer
  • NCI-C60582
  • Neocompensan
  • NSC 114022
  • NSC 142693
  • Peragal ST
  • Peregal ST
  • Periston
  • Periston-N
  • Peviston
  • Plasdone
  • Plasdone 4
  • Plasdone K 29-32
  • Plasdone K-26/28
  • Plasdone No. 4
  • Plasdone XL
  • Plasmosan
  • Polividona
  • Polividona [INN-Spanish]
  • Polividone
  • Polividone [DCIT]
  • Poly(1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl), alpha-hydro-omega-((4-(iodo-(sup 131)I)phenyl)methyl)-
  • Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)
  • Poly(1-ethenyl-2-pyrrolidinone)
  • Poly(1-vinyl-2-pyrrolidinone)
  • Poly(1-vinyl-2-pyrrolidinone) homopolymer
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.1
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.2
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.3
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.4
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.5
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.6
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.7
  • Poly(1-vinyl-2-pyrrolidone)
  • Poly(1-vinylpyrrolidinone)
  • Poly(N-vinyl-2-pyrrolidinone)
  • Poly(N-vinyl-2-pyrrolidone)
  • Poly(N-vinylbutyrolactam)
  • Poly(N-vinylpyrrolidinone)
  • Poly(N-vinylpyrrolidone)
  • Poly(vinylpyrrolidinone)
  • Poly-N-vinyl pyrrolidone
  • Polyclar A. T.
  • Polyclar AT
  • Polyclar H
  • Polyclar L
  • Polyclar-AT
  • Polygyl
  • Polyplasdone
  • Polyplasdone XL
  • Polyvidone
  • Polyvidonum
  • Polyvidonum [INN-Latin]
  • Polyvinylpyrrolidone
  • Povidone
  • Povidone (usp xix)
  • Povidone K 30
  • Protagent
  • PVP
  • PVP 1
  • PVP 2
  • PVP 3
  • PVP 4
  • PVP 40
  • PVP 5
  • PVP 6
  • PVP 7
  • PVP K 3
  • PVP-K 15
  • PVP-K 30
  • PVP-K 60
  • PVP-K 90
  • PVPP
  • Sauflon
  • Subtosan
  • Toxobin
  • UNII-2S7830E561
  • UNII-333AG72FWJ
  • UNII-40UAA97IT9
  • UNII-68401960MK
  • UNII-6B46OH7T95
  • UNII-C67P1734QJ
  • UNII-E54VE15114
  • UNII-FZ989GH94E
  • UNII-H7AGY1OJO8
  • UNII-K0KQV10C35
  • UNII-RDH86HJV5Z
  • UNII-SZR7Z3Q2YH
  • UNII-U725QWY32X
  • Vinisil
  • Vinylpyrrolidinone polymer
  • Vinylpyrrolidone polymer

Systematic Names

  • 2-Pyrrolidinone, 1-ethenyl-, homopolymer
  • 2-Pyrrolidinone, 1-vinyl-, polymers (8CI)
  • Poly(1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl), alpha-hydro-omega-((4-(iodo-(sup 131)I)phenyl)methyl)-
  • Poly(1-vinyl-2-pyrrolidinone) homopolymer
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.1
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.2
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.3
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.4
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.5
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.6
  • Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.7
  • Polyvinylpyrrolidone

Superlist Names

  • Poly(vinylpyrrolidone), minimum number average molecular weight (in amu), 4,000
  • Povidone

Mixture Names

  • Refresh
  • Soothe
  • Tears Plus

Registry Numbers

CAS Registry Number

  • 9003-39-8

FDA UNIIs

  • 2S7830E561
  • 333AG72FWJ
  • 40UAA97IT9
  • 68401960MK
  • 6B46OH7T95
  • C67P1734QJ
  • E54VE15114
  • FZ989GH94E
  • H7AGY1OJO8
  • K0KQV10C35
  • RDH86HJV5Z
  • SZR7Z3Q2YH
  • U725QWY32X

Other Registry Numbers

  • 111214-46-1
  • 116404-61-6
  • 1173909-53-9
  • 121414-75-3
  • 1229193-79-6
  • 1234714-82-9
  • 1303541-78-7
  • 1310675-91-2
  • 132778-04-2
  • 132778-05-3
  • 132834-20-9
  • 1337987-71-9
  • 1394151-52-0
  • 1431958-26-7
  • 153631-61-9
  • 1694674-42-4
  • 170473-90-2
  • 1918127-90-8
  • 2062651-26-5
  • 2083718-66-3
  • 2083718-67-4
  • 2088158-90-9
  • 2100274-29-9
  • 29386-94-5
  • 41724-41-8
  • 496908-06-6
  • 53026-73-6
  • 53026-74-7
  • 53200-27-4
  • 61932-72-7
  • 65931-56-8
  • 730985-60-1
  • 862983-74-2
  • 878051-55-9
  • 9015-62-7
  • 9080-59-5

System Generated Number

  • 0009003398

Molecular Formulas

Molecular Formula

  • (C6-H9-N-O)x-

Molecular Formula Fragments

  • C6-H9-N-O
  • COMPONENT

Structure Descriptors

Smiles

N1(C(CCC1)=O)[C@@H](C*)*

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 100gm/kg (100000mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse LD50 intraperitoneal 12gm/kg (12000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse LD50 oral > 40gm/kg (40000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 40, Pg. 164, 1967.
mouse LD50 unreported 16gm/kg (16000mg/kg)   Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 19, Pg. 212, 1985.
mouse LDLo oral 3gm/kg (3000mg/kg)   Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse LDLo oral 3gm/kg (3000mg/kg)   Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse LDLo oral 5gm/kg (5000mg/kg)   Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
rabbit LD50 oral 1040mg/kg (1040mg/kg)   Veterinariya. Veterinary Science. Vol. 61(12), Pg. 68, 1985.
rat LD50 oral 100gm/kg (100000mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.