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Substance Name: Carboxymethylcellulose sodium [USP]
RN: 9004-32-4
InChIKey: DPXJVFZANSGRMM-UHFFFAOYSA-N

Notes

  • A cellulose derivative which is a beta-(1,4)-D-glucopyranose polymer. It is used as a bulk laxative and as an emulsifier and thickener in cosmetics and pharmaceuticals and as a stabilizer for reagents.
  • A cellulose derivative which is a Beta-(1->4)-D-glucopyranose polymer. It is used as a bulk laxative and as an emulsifier and thickener in cosmetics and pharmaceuticals and as a stabilizer for reagents.
  • Used in therapy of oral mucosal ulcers.

Molecular Formula

  • C2-H4-O3.x-Na.x-Unspecified

Molecular Weight

  • 263.1964
 

Classification Codes

  • Drug Carriers
  • Gastrointestinal Agents
  • Laxatives
  • Pharmaceutic Aid (Suspending Agent)
  • Pharmaceutic Aid (Tablet Excipient)
  • Pharmaceutic Aid (Viscosity-Increasing Agent)
  • Reproductive Effect
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
  • Tumor Data
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Names and Synonyms

Name of Substance

  • Carboxymethyl cellulose
  • Carboxymethylcellulose sodium
  • Carboxymethylcellulose sodium [USP]
  • Cellulose gum
  • Cellulose, carboxymethyl ether
  • Orabase
  • Sodium carboxymethyl cellulose
  • Sodium CMC

MeSH Heading

  • Carboxymethylcellulose sodium

Synonyms

  • 7H3SF
  • AC-Di-sol. NF
  • Aku-W 515
  • Aquacel
  • Aquaplast
  • Avicel RC/CL
  • B 10
  • B 10 (Polysaccharide)
  • Blanose BS 190
  • Blanose BWM
  • Camellose gum
  • Carbose 1M
  • Carboxymethylcellulose sodium
  • Carboxymethylcellulose sodium salt
  • Carboxymethylcellulose sodium, low-substituted
  • Carmellose gum
  • Carmellose sodium
  • Carmellose sodium, low-substituted
  • Carmethose
  • CCRIS 3653
  • Cellofas
  • Cellofas B
  • Cellofas B5
  • Cellofas B50
  • Cellofas B6
  • Cellofas C
  • Cellogel C
  • Cellogen 3H
  • Cellogen PR
  • Cellogen WS-C
  • Cellpro
  • Cellufix FF 100
  • Cellufresh
  • Cellugel
  • Cellulose carboxymethyl ether sodium salt
  • Cellulose glycolic acid, sodium salt
  • Cellulose gum
  • Cellulose sodium glycolate
  • Cellulose, carboxymethyl ether, sodium salt, low-substituted
  • Celluvisc
  • CM-Cellulose sodium salt
  • CMC
  • CMC 2
  • CMC 3M5T
  • CMC 41A
  • CMC 4H1
  • CMC 4M6
  • CMC 7H
  • CMC 7H3SF
  • CMC 7L1
  • CMC 7M
  • CMC 7MT
  • CMC sodium salt
  • Collowel
  • Copagel PB 25
  • Courlose A 590
  • Courlose A 610
  • Courlose A 650
  • Courlose F 1000G
  • Courlose F 20
  • Courlose F 370
  • Courlose F 4
  • Courlose F 8
  • Daicel 1150
  • Daicel 1180
  • Edifas B
  • Ethoxose
  • Fine Gum HES
  • Glikocel TA
  • KMTs 212
  • KMTs 300
  • KMTs 500
  • KMTs 600
  • Lovosa
  • Lovosa 20alk.
  • Lovosa TN
  • Lucel (polysaccharide)
  • Majol PLX
  • Modocoll 1200
  • NaCm-cellulose salt
  • Nymcel S
  • Nymcel slc-T
  • Nymcel ZSB 10
  • Nymcel ZSB 16
  • Polyfibron 120
  • Refresh Plus, Cellufresh Formula
  • S 75M
  • Sanlose SN 20A
  • Sarcell tel
  • Sodium carboxmethylcellulose
  • Sodium carboxymethyl cellulose
  • Sodium carboxymethylcellulose
  • Sodium cellulose glycolate
  • Sodium CM-cellulose
  • Sodium CMC
  • Sodium glycolate cellulose
  • Sodium salt of carboxymethylcellulose
  • Tylose 666
  • Tylose C
  • Tylose C 1000P
  • Tylose C 30
  • Tylose C 300
  • Tylose C 600
  • Tylose CB 200
  • Tylose CB series
  • Tylose CBR 400
  • Tylose CBR series
  • Tylose CBS 30
  • Tylose CBS 70
  • Tylose CR
  • Tylose CR 50
  • Tylose DKL
  • UNII-0891BL4S3D
  • UNII-0Z2R7OG99L
  • UNII-1RD48779FJ
  • UNII-379M03VC9O
  • UNII-4J4P6L645M
  • UNII-6YYV7VRE59
  • UNII-6ZQ8V6YVNK
  • UNII-72QQR5RYU4
  • UNII-75KU4500GF
  • UNII-8UX21M67IJ
  • UNII-8W25JI0G3V
  • UNII-93O70285VH
  • UNII-97W605BIK0
  • UNII-99H65D77XY
  • UNII-D7SXM450NR
  • UNII-E0DNV5JJHX
  • UNII-FC40A8XAJ3
  • UNII-K679OBS311
  • UNII-KX442849T5
  • UNII-M8VP63K8FU
  • UNII-M9J9397QWS
  • UNII-R05Y0B55JY
  • UNII-RYZ9SHL900
  • UNII-S5517JT8YS
  • UNII-V5U74HSL76
  • UNII-X075FT70UI
  • UNII-Y3R0RA1Q8S
  • UNII-YGX74DKE74
  • UNII-ZY4732LP1O
  • Unisol RH

Systematic Names

  • Carboxymethyl cellulose, sodium salt
  • Cellulose, carboxymethyl ether, sodium salt
  • Orabase

Superlist Names

  • Cellulose carboxymethyl ether, sodium salt
  • Sodium carboxymethyl cellulose

Registry Numbers

CAS Registry Number

  • 9004-32-4

FDA UNIIs

  • 0891BL4S3D
  • 0Z2R7OG99L
  • 1RD48779FJ
  • 379M03VC9O
  • 4J4P6L645M
  • 6YYV7VRE59
  • 6ZQ8V6YVNK
  • 72QQR5RYU4
  • 75KU4500GF
  • 8UX21M67IJ
  • 8W25JI0G3V
  • 93O70285VH
  • 97W605BIK0
  • 99H65D77XY
  • D7SXM450NR
  • E0DNV5JJHX
  • FC40A8XAJ3
  • K679OBS311
  • KX442849T5
  • M8VP63K8FU
  • M9J9397QWS
  • R05Y0B55JY
  • RYZ9SHL900
  • S5517JT8YS
  • V5U74HSL76
  • X075FT70UI
  • Y3R0RA1Q8S
  • YGX74DKE74
  • ZY4732LP1O

Other Registry Numbers

  • 1012064-31-1
  • 117385-93-0
  • 1262215-38-2
  • 12624-09-8
  • 1296213-64-3
  • 1422717-46-1
  • 1428980-42-0
  • 147881-80-9
  • 1610028-94-8
  • 1610029-04-3
  • 198084-97-8
  • 2014388-59-9
  • 2072854-79-4
  • 2131127-75-6
  • 247080-55-3
  • 37231-14-4
  • 37231-15-5
  • 404943-62-0
  • 454679-81-3
  • 50642-44-9
  • 54018-17-6
  • 55607-96-0
  • 64103-90-8
  • 654655-39-7
  • 73699-63-5
  • 80296-93-1
  • 81209-86-1
  • 82197-79-3
  • 854036-84-3
  • 9045-95-8
  • 9085-26-1

System Generated Number

  • 0009004324

Molecular Formulas

Molecular Formula

  • C2-H4-O3.x-Na.x-Unspecified

Molecular Formula Fragments

  • C2-H4-O3
  • COMPONENT
  • Na
  • Unspecified

Structure Descriptors

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);

InChIKey

DPXJVFZANSGRMM-UHFFFAOYSA-N

Smiles

[Na].CC(=O)O.OCC(O)C(O)C(O)C(O)C=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 16000mg/kg (16000mg/kg)   Food Research. Vol. 13, Pg. 29, 1948.
mouse LD50 oral > 27gm/kg (27000mg/kg)   Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
rabbit LD50 oral > 27gm/kg (27000mg/kg)   Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
rabbit LD50 skin > 2gm/kg (2000mg/kg)   Toxicology Letters. Vol. (Suppl), Pg. 243, 1992.
rat LC50 inhalation > 5800mg/m3/4H (5800mg/m3)   Toxicology Letters. Vol. (Suppl), Pg. 243, 1992.
rat LD50 oral 27000mg/kg (27000mg/kg)   Food Research. Vol. 13, Pg. 29, 1948.