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Substance Name: Iron dextran [USP]
RN: 9004-66-4
UNII: 95HR524N2M
Note
- A complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Molecular Formula
- Unspecified
Molecular Weight
- 286.0126
Classification Codes
Classification Codes
- Drug / Therapeutic Agent
- Hematinic
- Hematinics
- Hematologic Agents
- Human Data
- Reproductive Effect
- Tumor Data
Superlist Classification Codes
- Overall Carcinogenic Evaluation: Group 2B
- Reasonably Anticipated to be a Carcinogen
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Iron dextran
- Iron dextran [USP]
- Iron-dextran complex
MeSH Heading
- Iron-dextran complex
Synonyms
- A 100
- A 100 (Pharmaceutical)
- B 75
- CCRIS 347
- Chinofer
- Dexferrum
- Dextran iron complex
- Dextrofer 75
- Eisendextran
- Eisendextran [German]
- Fe-Dextran
- Fenate
- Ferdex 100
- Ferric dextran
- Ferridextran
- Ferrodextran
- Ferroglucin
- Ferroglukin 75
- HSDB 5102
- Imferon
- Imposil
- Infed
- Iro-Jex
- Iron dextran
- Iron dextran complex
- Iron dextran injection
- Iron hydrogenated dextran
- Iron-dextran complex
- Iron-Gard
- Ironorm injection
- Myofer 100
- Polyfer
- Proferdex
- Prolongal
- RCRA waste number U139
- UNII-95HR524N2M
- Ursoferran
Systematic Names
- Imferon
- Iron dextran
Superlist Names
- Iron dextran
- Iron dextran complex
- Iron-dextran complex
Registry Numbers
CAS Registry Number
- 9004-66-4
FDA UNII
- 95HR524N2M
Other Registry Numbers
- 11129-47-8
- 37318-94-8
- 37349-14-7
- 50643-00-0
- 53858-58-5
- 8050-93-9
- 9009-88-5
- 9044-58-0
- 9061-47-6
System Generated Number
- 0009004664
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intramuscular | > 450mg(Fe)/kg (450mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| mouse | LD50 | intravenous | 460mg(Fe)/kg (460mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 18, Pg. 149, 1961. | |
| mouse | LD50 | oral | 1gm(Fe)/kg (1000mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 24, Pg. 352, 1965. | |
| rabbit | LD | intramuscular | > 690mg(Fe)/kg (690mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| rabbit | LDLo | intravenous | 500mg(Fe)/kg (500mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| rat | LD50 | intraperitoneal | 3gm(Fe)/kg (3000mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
| rat | LDLo | intramuscular | 1617mg(Fe)/kg (1617mg/kg) | Acta Veterinaria Vol. 29, Pg. 21, 1979. |