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Substance Name: Polysorbate 60 [USAN:INN:BAN:NF]
RN: 9005-67-8
InChIKey: DEKFZWMENCCOFU-LIKAHPKFSA-N

Classification Codes

  • Pharmaceutic Aid (Surfactant)
  • Reproductive Effect
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
  • Tumor Data

Molecular Formulas

  • C64-H126-O26
  • Unspecified

Molecular Weight

  • 606.8318
 
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Names and Synonyms

Name of Substance

  • PEG-3 Sorbitan stearate
  • PEG-40 Sorbitan stearate
  • PEG-6 Sorbitan stearate
  • PEG-60 Sorbitan stearate
  • Polyethylene glycol (3) sorbitan monostearate
  • Polyethylene glycol 2000 sorbitan stearate
  • Polyethylene glycol 300 sorbitan monostearate
  • Polyethylene glycol 3000 sorbitan monostearate
  • Polyoxyethylene (20) sorbitan monostearate
  • Polyoxyethylene (3) sorbitan monostearate
  • Polyoxyethylene (4) sorbitan monostearate
  • Polyoxyethylene (40) sorbitan stearate
  • Polyoxyethylene (6) sorbitan monostearate
  • Polyoxyethylene (60) sorbitan monostearate
  • Polysorbate 60
  • Polysorbate 60 [USAN:INN:BAN:NF]
  • Polysorbate 61
  • Sorbimacrogol stearate 300
  • Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.

Synonyms

  • CCRIS 702
  • EC 500-020-4
  • FEMA No. 2916
  • Glycosperse S-20
  • Peg sorbitan stearate
  • Peg-20 sorbitan stearate
  • Polyoxyethylene 20 sorbitan monostearate
  • Polyoxyethylene sorbitan monostearate
  • Polyoxyethylene-40-sorbitan monostearate
  • Polysorbate 60
  • Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
  • Sorbitan, monostearate, polyoxyethylene derivs.
  • Tween 60
  • UNII-073G38N8GC
  • UNII-3453J8557N
  • UNII-90SOR12GHG
  • UNII-CAL22UVI4M
  • UNII-HD40WR33LC
  • UNII-X61U1UH01B

Systematic Names

  • Polyoxyethylene sorbitan monostearate
  • Sorbitan monostearate, ethoxylated
  • Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
  • Sorbitan, monostearate polyoxyethylene deriv.

Superlist Names

  • Polyoxyethylene sorbitan monostearate
  • Polysorbate 60
  • Sorbitan, monostearate, polyoxyethylene derivs.

Registry Numbers

CAS Registry Number

  • 9005-67-8

FDA UNIIs

  • 073G38N8GC
  • 3453J8557N
  • 90SOR12GHG
  • CAL22UVI4M
  • HD40WR33LC
  • X61U1UH01B

Other Registry Numbers

  • 1014699-55-8
  • 1129451-61-1
  • 1176304-49-6
  • 1196790-24-5
  • 1241391-69-4
  • 127313-74-0
  • 1340-82-5
  • 136032-14-9
  • 141704-73-6
  • 180473-24-9
  • 64696-12-4
  • 69431-67-0
  • 9011-31-8
  • 9015-59-2
  • 902145-49-7
  • 9087-92-7
  • 91727-27-4
  • 93906-96-8

System Generated Number

  • 0009005678

Structure Descriptors

InChI

1S/C32H62O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-26-28(38-21-18-33)32-31(41-23-20-35)29(27-42-32)39-22-19-34/h28-29,31-35H,2-27H2,1H3/t28-,29-,31+,32-/m1/s1

InChIKey

DEKFZWMENCCOFU-LIKAHPKFSA-N

Smiles

CCCCCCCCCCCCCCCCCC(=O)OCCOC[C@H]([C@@H]1[C@H]([C@@H](CO1)OCCO)OCCO)OCCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intravenous 1gm/kg (1000mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 685, 1956.
rat LD50 intravenous 1220mg/kg (1220mg/kg)   FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 254, 1974.
rat LD50 oral > 60mL/kg (60mL/kg)   Food Research. Vol. 21, Pg. 348, 1956.
rat LDLo intraperitoneal > 4gm/kg (4000mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959.