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Substance Name: Droxicam [INN]
RN: 90101-16-9
UNII: F24ADO1E2D
InChIKey: OEHFRZLKGRKFAS-UHFFFAOYSA-N

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Peripheral Nervous System Agents
  • Sensory System Agents

Molecular Formula

  • C16-H11-N3-O5-S

Molecular Weight

  • 357.3449
 
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Names and Synonyms

Name of Substance

  • Droxicam
  • Droxicam [INN]

Synonyms

  • 5-Methyl-3-(2-pyridinyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide
  • 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide
  • BRN 6006252
  • Droxicam
  • Droxicamum
  • Droxicamum [Latin]
  • E 318
  • UNII-F24ADO1E2D

Systematic Names

  • 2H,5H-1,3-Oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione, 5-methyl-3-(2-pyridinyl)-, 6,6-dioxide
  • 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)-dione 6,6-dioxide

Registry Numbers

CAS Registry Number

  • 90101-16-9

FDA UNII

  • F24ADO1E2D

System Generated Number

  • 0090101169

Structure Descriptors

InChI

1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3

InChIKey

OEHFRZLKGRKFAS-UHFFFAOYSA-N

Smiles

CN1c2c(oc(=O)n(c2=O)c3ccccn3)-c4ccccc4S1(=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 6192mg/kg (6192mg/kg)   United States Patent Document. Vol. #4563452,
rat LD50 oral 1434mg/kg (1434mg/kg)   United States Patent Document. Vol. #4563452,