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Substance Name: Subtilisins
RN: 9014-01-1
UNII: 0ZP13EBC5Y

Note

  • A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.

Molecular Formula

  • Unspecified
 

Classification Codes

Classification Codes

  • Skin / Eye Irritant
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)

Superlist Classification Code

  • Ceiling 0.00006 mg/m3 (as active crystalline enzyme)
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Links to Resources

Names and Synonyms

Name of Substance

  • Subtilisins

MeSH Heading

  • Subtilisin

Synonyms

  • Alcalase
  • ALK-enzyme
  • Alkalase AF 2.4
  • Bacillopeptidase A
  • Bacillopeptidase B
  • Bacillus subtilis enzyme fermentation product
  • Bioprase
  • Bioprotease B 10L
  • Chirazyme P 1
  • Colistinase
  • Dafazyme PR B
  • E.C. 3.4.21.14
  • E.C. 3.4.4.16
  • EC 232-752-2
  • EINECS 232-752-2
  • Esperase
  • Extretex
  • Genenase
  • HSDB 7921
  • Maxatase
  • Nagarse
  • SP 266
  • Subtilisin bpn'
  • Subtilisin carlsburg
  • Subtilisin NOVO
  • Subtilopeptidase A
  • Subtilopeptidase B
  • Subtilopeptidase bpn'
  • Subtilopeptidase C
  • Thermoase PC-10
  • UNII-0ZP13EBC5Y

Systematic Names

  • Bacillus subtilis carlsberg
  • Subtilisin

Superlist Names

  • Proteolytic enzymes
  • Subtilisin
  • Subtilisins
  • Subtilisins (proteolytic enzymes as 100% pure crystalline enzyme)

Registry Numbers

CAS Registry Number

  • 9014-01-1

FDA UNII

  • 0ZP13EBC5Y

Other Registry Numbers

  • 104645-85-4
  • 12626-20-9
  • 12770-87-5
  • 1349805-21-5
  • 148093-32-7
  • 179530-31-5
  • 196414-34-3
  • 213972-06-6
  • 2392-42-9
  • 9028-05-1
  • 9031-73-6
  • 9045-36-7
  • 9063-47-2
  • 9067-41-8

System Generated Number

  • 0009014011

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 3700mg/kg (3700mg/kg)   Food and Cosmetics Toxicology. Vol. 7, Pg. 581, 1969.