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Substance Name: Pyruvate Carboxylase
RN: 9014-19-1


  • A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC
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Names and Synonyms

Name of Substance

  • Pyruvate Carboxylase

MeSH Heading

  • Pyruvate Carboxylase


  • Carboxylase, pyruvate

Systematic Name

  • Pyruvate:carbon-dioxide ligase (ADP-forming)

Registry Numbers

CAS Registry Number

  • 9014-19-1

System Generated Number

  • 0009014191