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Substance Name: Polyphloretin phosphate
RN: 9014-72-6

Note

  • A polymeric mixture of polyesters of phosphoric acid and phloretin. It blocks some cellular responses to prostaglandins.

Classification Codes

  • Hormone Antagonists
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Prostaglandin Antagonists
  • Reproductive Effect

Molecular Weight

  • 372.264
 
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Names and Synonyms

Name of Substance

  • Polyphloretin phosphate

MeSH Heading

  • Polyphloretin phosphate

Synonyms

  • AHly
  • LEO 101
  • LEO 101K
  • LEO 1235g
  • LEO 1259a
  • LEO 1261a
  • Polyphloretin phosphate

Systematic Names

  • 1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, phosphate, homopolymer (9CI)
  • 1-Propanone, 3-(hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, phosphate, homopolymer
  • Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-, phosphate, polyesters

Registry Numbers

CAS Registry Number

  • 9014-72-6

System Generated Number

  • 0009014726

Structure Descriptors

Smiles

C(c1c(cc(O)cc1O)O)(CCc1ccc(cc1)O)=O.P(=O)(O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 1gm/kg (1000mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 42, Pg. 660, 1990.