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Substance Name: Glutamate-Cysteine Ligase
RN: 9023-64-7


  • One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of gamma-glutamylcysteine from glutamate and cysteine in the presence of ATP with the formation of ADP and orthophosphate. EC
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Names and Synonyms

Name of Substance

  • Glutamate-Cysteine Ligase

MeSH Heading

  • Glutamate-Cysteine Ligase


  • gamma glutamyl cysteine synthetase
  • gamma-glutamyl-cysteine synthetase
  • Glutamate cysteine Ligase
  • Glutamylcysteine synthetase
  • Ligase, glutamate-cysteine
  • Synthetase, gamma-glutamyl-cysteine
  • Synthetase, glutamylcysteine

Systematic Name

  • L-Glutamate:L-cysteine gamma-ligase (ADP-forming)

Registry Numbers

CAS Registry Number

  • 9023-64-7

System Generated Number

  • 0009023647