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Substance Name: Glutamate Decarboxylase
RN: 9024-58-2

Note

  • A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.
 
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Names and Synonyms

Name of Substance

  • Glutamate Decarboxylase

MeSH Heading

  • Glutamate Decarboxylase

Synonyms

  • Alum-GAD
  • Cysteic acid decarboxylase
  • Diamyd
  • E.C. 4.1.1.11
  • E.C. 4.1.1.15
  • EINECS 232-782-6
  • GAD-Alum
  • gamma Glutamate decarboxylase
  • Glutamate Carboxy-Lyase
  • Glutamic acid decarboxylase
  • L-Glutamate alpha-decarboxylase
  • L-Glutamate decarboxylase
  • L-Glutamic acid decarboxylase

Systematic Name

  • Decarboxylase, glutamate

Registry Numbers

CAS Registry Number

  • 9024-58-2

Other Registry Numbers

  • 72750-60-8
  • 9024-56-0
  • 9024-71-9

System Generated Number

  • 0009024582