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Substance Name: Montirelin [INN]
RN: 90243-66-6
UNII: 30MUJ6YYUY
InChIKey: RSHMQGIMHQPMEB-IXOXFDKPSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C17-H24-N6-O4-S
Molecular Weight
- 408.4806
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Names and Synonyms
Name of Substance
- Montirelin [INN]
Synonyms
- (-)-N-(((3R,6S)-6-Methyl-5-oxo-3-thiomorpholinyl)carbonyl)-L-histidyl-L-prolinamide
- (3R-cis)-N-((6-Methyl-5-oxo-3-thiomorpholinyl)carbonyl)-L-histidyl-L-prolinamide
- CCRIS 7571
- CG 3703
- CNK 602A
- CNK-603
- L-Prolinamide, (2R)-2-mercaptopropanoyl-L-cysteinyl-L-histidyl-, cyclic (1-2)-sulfide
- Montirelin
- Montirelina
- Montirelina [Spanish]
- Montireline
- Montireline [French]
- Montirelinum
- Montirelinum [Latin]
- N-(((3R,6R)-6-Methyl-5-oxo-3-thiomorpholinyl)carbonyl)-L-histidyl-L-prolinamide
- NS 3
- UNII-30MUJ6YYUY
Systematic Names
- L-Prolinamide, (3R,6R)-6-methyl-5-oxo-3-thiomorpholinecarbonyl-L-histidyl-
- L-Prolinamide, N-((6-methyl-5-oxo-3-thiomorpholinyl)carbonyl)-L-histidyl-, (3R-cis)-
- Montirelin
- N-(((3R,6R)-6-Methyl-5-oxo-3-thiomorpholinyl)carbonyl)-L-histidyl-L-prolinamide
Registry Numbers
CAS Registry Number
- 90243-66-6
FDA UNII
- 30MUJ6YYUY
System Generated Number
- 0090243666
Structure Descriptors
InChI
InChI=1S/C17H24N6O4S/c1-9-15(25)22-12(7-28-9)16(26)21-11(5-10-6-19-8-20-10)17(27)23-4-2-3-13(23)14(18)24/h6,8-9,11-13H,2-5,7H2,1H3,(H2,18,24)(H,19,20)(H,21,26)(H,22,25)/t9-,11+,12+,13+/m1/s1InChIKey
RSHMQGIMHQPMEB-IXOXFDKPSA-NSmiles
C[C@H]1SC[C@H](NC1=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD | oral | > 5gm/kg (5000mg/kg) | United States Patent Document. Vol. #4877784, | |
mouse | LDLo | intravenous | 125mg/kg (125mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Journal of Toxicological Sciences. Vol. 20(Suppl, |