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Substance Name: Elosulfase alfa [USAN:INN]
RN: 9025-60-9
UNII: ODJ69JZG85

Note

  • BMN-100 and BMN 110 are recombinant GALNS; RefSeq NM_000512.

    Daily Med: Vimizim is a formulation of elosulfase alfa, which is a purified human enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. Human N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) is a hydrolytic lysosomal glycosaminoglycan-specific enzyme that hydrolyzes sulfate from either galactose-6-sulfate or N-acetyl-galactosamine-6-sulfate on the non-reducing ends of the glycosaminoglycans keratan sulfate (KS) and chondroitin-6-sulfate (C6S).

Molecular Formula

  • C5020-H7588-N1364-O1418-S34
 

Names and Synonyms

Name of Substance

  • Elosulfase alfa [USAN:INN]

Synonyms

  • BMN 110
  • Chondroitin 6-sulfatase
  • Chondroitin sulfatase
  • Chondroitin sulfate sulfatase
  • Chondroitinase
  • Chondrosulfatase
  • E.C. 3.1.6.4
  • Elosulfase alfa
  • rhGALNS
  • UNII-ODJ69JZG85
  • Vimizim

Systematic Name

  • Sulfatase, chondroitin

Registry Numbers

CAS Registry Number

  • 9025-60-9

FDA UNII

  • ODJ69JZG85

Other Registry Number

  • 9079-83-8

System Generated Number

  • 0009025609