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Substance Name: Methenyltetrahydrofolate Cyclohydrolase
RN: 9027-97-8


  • An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms this enzyme also includes METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP) and FORMATE-TETRAHYDROFOLATE LIGASE activities.
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Names and Synonyms

Name of Substance

  • Methenyltetrahydrofolate Cyclohydrolase

MeSH Heading

  • Methenyltetrahydrofolate Cyclohydrolase


  • 5,10 Methenyltetrahydrofolate Cyclohydrolase
  • 5,10 MTHF Cyclohydrolase
  • 5,10-Methenyltetrahydrofolate 5-Hydrolase (Decyclizing)
  • 5,10-Methenyltetrahydrofolate Cyclohydrolase
  • 5,10-MTHF Cyclohydrolase
  • Cyclohydrolase, 5,10-Methenyltetrahydrofolate
  • Cyclohydrolase, 5,10-MTHF
  • Cyclohydrolase, Methenyltetrahydrofolate

Registry Numbers

CAS Registry Number

  • 9027-97-8

System Generated Number

  • 0009027978