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Substance Name: Squalene Monooxygenase
RN: 9029-62-3


  • The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
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Names and Synonyms

Name of Substance

  • Squalene Monooxygenase

MeSH Heading

  • Squalene Monooxygenase


  • Epoxidase, Squalene
  • Monooxygenase, Squalene
  • Squalene Epoxidase
  • Squalene Monooxygenase (2,3-Epoxidizing)

Registry Numbers

CAS Registry Number

  • 9029-62-3

System Generated Number

  • 0009029623