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Substance Name: Tilactase [INN:JAN]
RN: 9031-11-2

Note

  • A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Drug / Therapeutic Agent
  • TSCA Flag XU (Exempt from Reporting under the Inventory Update Rule)
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Links to Resources

Names and Synonyms

Name of Substance

  • Tilactase [INN:JAN]

MeSH Heading

  • beta-Galactosidase

Synonyms

  • beta-D-Lactosidase
  • beta-Galactosidase
  • beta-Lactosidase
  • Biolacta
  • Dairyaid
  • E.C. 3.2.1.23
  • EINECS 232-864-1
  • Galantase
  • Hydrolact
  • Lactaid
  • Lactase
  • Lactosylceramidase II
  • Lactozym
  • Maxilact
  • Oryzatym
  • S 2107
  • SL 396
  • Sumiklat
  • Tilactasa
  • Tilactasa [Spanish]
  • Tilactase
  • Tilactasum
  • Tilactasum [Latin]
  • UNII-37515NWH9U
  • UNII-G9S0VV191I

Systematic Names

  • beta-D-Galactosidase
  • Galactosidase, beta-

Superlist Name

  • Lactase enzyme preparation from Candida pseudotropicalis

Registry Numbers

CAS Registry Number

  • 9031-11-2

FDA UNIIs

  • 37515NWH9U
  • G9S0VV191I

Other Registry Number

  • 121854-92-0

System Generated Number

  • 0009031112

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD oral > 30mg/kg (30mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 729, 1970.
mouse LD50 intraperitoneal 630mg/kg (630mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 729, 1970.
mouse LD50 subcutaneous 1470mg/kg (1470mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 729, 1970.
rat LD oral > 20mg/kg (20mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 725, 1970.
rat LD50 intraperitoneal 660mg/kg (660mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 725, 1970.
rat LD50 subcutaneous 4090mg/kg (4090mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 725, 1970.